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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Helq
helicase, POLQ-like
MGI:2176740
28 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Helqem1(IMPC)Mbp/Helqem1(IMPC)Mbp
C57BL/6N-Helqem1(IMPC)Mbp/MbpMmucd 		abnormal caudal vertebrae morphology J:211773
abnormal eye morphology J:211773
abnormal kidney morphology J:211773
abnormal testis morphology J:211773
decreased bone mineral content J:211773
decreased lean body mass J:211773
female infertility J:211773
increased total body fat amount J:211773
male infertility J:211773
small kidney J:211773
small testis J:211773
Helqem1Eljt/Helqem1Eljt
C57BL/6J-Helqem1Eljt 		normal reproductive system phenotype J:347863
HelqGt(RRF112)Byg/Helq+
involves: 129P2/OlaHsd * C57BL/6 		abnormal ovary morphology J:206104
absent mature ovarian follicles J:206104
decreased mature ovarian follicle number J:206104
increased Harderian gland tumor incidence J:206104
increased intestinal adenoma incidence J:206104
increased pituitary adenoma incidence J:206104
ovary atrophy J:206104
ovary cyst J:206104
HelqGt(RRF112)Byg/HelqGt(RRF112)Byg
involves: 129P2/OlaHsd * C57BL/6 		abnormal spermatogonia morphology J:206104
decreased litter size J:206104
increased gland tumor incidence J:206104
increased granulosa cell tumor incidence J:206104
increased Harderian gland tumor incidence J:206104
increased mammary gland tumor incidence J:206104
increased ovary tumor incidence J:206104
increased pituitary adenoma incidence J:206104
ovary atrophy J:206104
ovary cyst J:206104
reduced fertility J:206104
small testis J:206104
testicular atrophy J:206104
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory