Dicer1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dicer1
dicer 1, ribonuclease type III
MGI:2177178

27 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Bcl2l11^tm1.1Ast/Bcl2l11^tm1.1Ast Dicer1^tm1Mmk/Dicer1^tm1Mmk Cd79a^tm1(cre)Reth/Cd79a⁺ involves: 129S1/Sv * BALB/c	decreased B cell number	J:135783
	decreased mature B cell number	J:135783
Bcl2l11^tm1Ast/Bcl2l11^tm1Ast Dicer1^tm1Bdh/Dicer1^tm1Bdh Aicda^tm1(cre)Njen/Aicda⁺ involves: 129S1/Sv * C57BL/6	abnormal B cell differentiation	J:181782
	decreased germinal center B cell number	J:181782
	decreased plasma cell number	J:181782
Cd79a^tm1(cre)Reth/Cd79a⁺ Dicer1^tm1Mmk/Dicer1^tm1Mmk Tg(BCL2)22Wehi/0 involves: BALB/c * C57BL/6JWehi * SJL/JWehi	decreased B cell number	J:135783
	decreased mature B cell number	J:135783
Cdkn2a^tm1Rdp/Cdkn2a^tm1Rdp Dicer1^tm1Snj/Dicer1^tm1Snj involves: 129/Sv * 129S7/SvEvBrd * C57BL/6 * SJL	increased cell proliferation	J:139257
Cdkn2a^tm1Rdp/Cdkn2a^tm1Rdp Dicer1^tm1Snj/Dicer1^tm1Snj involves: 129/Sv * 129S7/SvEvBrd * C57BL/6 * SJL	normal cellular phenotype	J:139257
Dicer1^tm1.1Doca/Dicer1^tm1.1Doca involves: 129P2/OlaHsd * BALB/cJ * C57BL/6	no abnormal phenotype detected	J:228491
Dicer1^tm1Bdh/Dicer1⁺ Yy1^tm2.1Yshi/Yy1⁺ Shh^{tm1(EGFP/cre)Cjt}/Shh⁺ involves: 129 * 129S4/SvJae * C57BL/6	normal respiratory system phenotype	J:239777
Dicer1^tm1Mmk/Dicer1^tm1Mmk Fgf9^tm1.1Fwan/Fgf9⁺ Shh^{tm1(EGFP/cre)Cjt}/Shh⁺ involves: 129 * 129S4/SvJaeSor * C57BL/6J	normal respiratory system phenotype	J:224791
Dicer1^tm1Mmk/Dicer1^tm1Mmk Fgf9^tm1.1Fwan/Fgf9^tm1.1Fwan Shh^{tm1(EGFP/cre)Cjt}/Shh⁺ involves: 129 * 129S4/SvJaeSor * C57BL/6J	normal respiratory system phenotype	J:224791
Dicer1^tm1Mmk/Dicer1^tm1Mmk Tg(IghelMD4)4Ccg/0 Cd79a^tm1(cre)Reth/Cd79a⁺ involves: BALB/c	decreased B cell number	J:135783
	decreased mature B cell number	J:135783
Dicer1^tm1Snj/Dicer1^tm1Snj Trp53^tm1Brd/Trp53^tm1Brd involves: 129S7/SvEvBrd * C57BL/6	increased cell proliferation	J:139257
Dicer1^tm1Snj/Dicer1^tm1Snj Trp53^tm1Brd/Trp53^tm1Brd involves: 129S7/SvEvBrd * C57BL/6	normal cellular phenotype	J:139257
Dicer1^tm1Snj/Dicer1^tm1Snj Trp53^tm1Brn/Trp53⁺ Tg(KRT5-cre/PGR)1Der/0 involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6N * FVB/N * ICR	increased basal cell carcinoma incidence	J:216813
	increased skin tumor incidence	J:216813
	premature death	J:216813
Dicer1^tm1Snj/Dicer1^tm1Snj Trp53^tm1Brn/Trp53^tm1Brn Tg(KRT5-cre/PGR)1Der/0 involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6N * FVB/N * ICR	abnormal epidermis stratum basale morphology	J:216813
	abnormal hair cycle	J:216813
	abnormal hair follicle morphology	J:216813
	abnormal hair shaft morphology	J:216813
	abnormal skin physiology	J:216813
	hypergranulosis	J:216813
	increased skin squamous cell carcinoma incidence	J:216813
	increased skin tumor incidence	J:216813
	premature death	J:216813
	progressive hair loss	J:216813
	thick epidermis	J:216813
Dicer1^tm1Tara/Dicer1^tm1Tara Pten^tm1Hwu/Pten^tm1Hwu Amhr2^tm3(cre)Bhr/Amhr2⁺ involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd	abnormal oviduct morphology	J:182161
	ascites	J:182161
	increased carcinoma incidence	J:182161
	increased metastatic potential	J:182161
	increased ovarian carcinoma incidence	J:182161
	premature death	J:182161
Dicer1^tm1Tara/Dicer1^tm1Tara Pten^tm1Hwu/Pten^tm1Hwu Trp53^tm2Tyj/Trp53⁺ Amhr2^tm3(cre)Bhr/Amhr2⁺ involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd	ascites	J:222579
	increased carcinoma incidence	J:222579
	increased metastatic potential	J:222579
	increased ovarian carcinoma incidence	J:222579
	premature death	J:222579
Dicer1^tm1Tara/Dicer1^tm1Tara Trp53^tm2Tyj/Trp53⁺ Amhr2^tm3(cre)Bhr/Amhr2⁺ involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd	normal neoplasm	J:222579

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