Cys1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cys1
cystin 1
MGI:2177632

39 phenotypes from 1 allele in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cys1^cpk/Cys1⁺ B6(Cg)-Cys1^cpk/J	abnormal cochlear inner hair cell morphology	J:1001
	abnormal organ of Corti morphology	J:1001
	abnormal pillar cell morphology	J:1001
	abnormal Reissner membrane morphology	J:1001
	absent cochlear outer hair cells	J:1001
	cochlear ganglion hypoplasia	J:1001
	increased or absent threshold for auditory brainstem response	J:1001
Cys1^cpk/Cys1⁺ C.B6(Cg)-Cys1^cpk	liver cyst	J:99616
Cys1^cpk/Cys1⁺ C.B6(Cg)-Cys1^cpk	liver fibrosis	J:99616
Cys1^cpk/Cys1⁺ involves: C57BL/6J * CD-1	kidney cyst	J:33739
	liver cyst	J:33739
	liver fibrosis	J:33739
Cys1^cpk/Cys1^cpk 129.B6-Cys1^cpk	increased kidney weight	J:116210
	kidney cyst	J:116210
	liver inflammation	J:116210
	pancreas cyst	J:116210
Cys1^cpk/Cys1^cpk B6(Cg)-Cys1^cpk/J	abnormal kidney corticomedullary boundary morphology	J:6718
	colorless urine	J:6718
	decreased hematocrit	J:9290
	distended abdomen	J:6718, J:31533
	enlarged kidney	J:6718, J:9290
	increased blood urea nitrogen level	J:6718, J:9290
	increased kidney weight	J:9290
	kidney cyst	J:6718, J:9290
	lethargy	J:6718
	polycystic kidney	J:31533
	postnatal lethality, complete penetrance	J:6718, J:31533
Cys1^cpk/Cys1^cpk B6(Cg)-Cys1^cpk/JUnc	colorless urine	J:7202
	distended abdomen	J:7202
	enlarged kidney	J:7202
	increased blood urea nitrogen level	J:7202
	increased circulating creatinine level	J:7202
	kidney cyst	J:7202
	lethargy	J:7202
	premature death	J:7202
	tremors	J:7202
Cys1^cpk/Cys1^cpk C.B6(Cg)-Cys1^cpk	absent pancreatic islets	J:99616
	biliary cyst	J:99616
	decreased body size	J:99616
	dilated bile duct	J:99616
	dilated pancreatic duct	J:99616
	enlarged kidney	J:99616
	increased blood urea nitrogen level	J:99616
	kidney cortex cyst	J:99616
	kidney cyst	J:99616
	liver fibrosis	J:99616
	pancreas fibrosis	J:99616
Cys1^cpk/Cys1^cpk D2J.B6(Cg)-Cys1^cpk	abnormal bile duct morphology	J:99620
	abnormal pancreatic acinus morphology	J:99620
	abnormal suckling behavior	J:99620
	absent pancreatic islets	J:99620
	dilated pancreatic duct	J:99620
	ectopic pancreatic acinar cells	J:99620
	enlarged kidney	J:99620
	increased blood urea nitrogen level	J:99620
	increased circulating creatinine level	J:99620
	increased kidney weight	J:99620
	kidney cyst	J:99620
	lethargy	J:99620
	liver fibrosis	J:99620
	pancreas fibrosis	J:99620
Cys1^cpk/Cys1^cpk involves: C57BL/6J * CD-1	biliary cyst	J:33739
	enlarged kidney	J:33739
	increased blood urea nitrogen level	J:33739
	kidney cyst	J:33739
	liver cyst	J:33739
	pancreas cyst	J:33739
	postnatal lethality	J:33739
	spleen hypoplasia	J:33739
	thymus hypoplasia	J:33739

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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