Pla2g15 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pla2g15
phospholipase A2, group XV
MGI:2178076

14 phenotypes from 3 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pla2g15^tm1.1Jash/Pla2g15^tm1.1Jash involves: 129S1/Sv * C57BL/6	abnormal heart morphology	J:111561
	abnormal kidney morphology	J:111561
	abnormal macrophage morphology	J:111561
	abnormal macrophage physiology	J:111561
	abnormal pulmonary alveolus morphology	J:111561
	abnormal spleen morphology	J:111561
	hepatic steatosis	J:111561
	increased macrophage cell number	J:111561
	increased macrophage derived foam cell number	J:111561
	increased spleen weight	J:111561
	normal reproductive system phenotype	J:111561
Pla2g15^tm1Jash/Pla2g15^tm1Jash involves: 129S1/Sv * C57BL/6	no abnormal phenotype detected	J:111561
Pla2g15^tm1Ytan/Pla2g15^tm1Ytan involves: 129S/SvEv	abnormal circulating cholesterol level	J:97471
Pla2g15^tm1Ytan/Pla2g15^tm1Ytan involves: 129S/SvEv	decreased susceptibility to atherosclerosis	J:97471

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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