Akap9 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Akap9
A kinase anchor protein 9
MGI:2178217

41 phenotypes from 4 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Akap9^mei2-5/Akap9^mei2-5 involves: 129S1/Sv	abnormal Sertoli cell development	J:198499
	abnormal spermatocyte morphology	J:198499
	abnormal spermatogenesis	J:198499
	azoospermia	J:198499
Akap9^mei2-5/Akap9^mei2-5 involves: 129S1/Sv * C57BL/6	abnormal testis morphology	J:86161
	arrest of male meiosis	J:86161
	male infertility	J:86161
Akap9^mei2-5/Akap9^repro12 involves: 129S1/Sv * C57BL/6J	abnormal spermatogenesis	J:198499
	arrest of spermatogenesis	J:198499
	azoospermia	J:198499
Akap9^repro12/Akap9^repro12 involves: C3HeB/FeJ * C57BL/6J	abnormal seminiferous tubule morphology	J:92463
	decreased seminal vesicle weight	J:92463
	decreased testis weight	J:92463
	globozoospermia	J:92463
	male infertility	J:92463
	oligozoospermia	J:92463
Akap9^repro12/Akap9^repro12 involves: C57BL/6J	arrest of spermatogenesis	J:198499
Akap9^repro12/Akap9^{tm1b(KOMP)Wtsi} involves: C57BL/6J * C57BL/6N * FVB/N	abnormal spermatogenesis	J:198499
	azoospermia	J:198499
Akap9^{tm1a(KOMP)Wtsi}/Akap9⁺ B6JTyr;B6N-Akap9^{tm1a(KOMP)Wtsi}/Wtsi	abnormal head morphology	J:175295
	decreased body weight	J:175295
	decreased circulating calcium level	J:175295
	decreased circulating cholesterol level	J:175295
	decreased circulating fructosamine level	J:175295
	decreased circulating HDL cholesterol level	J:175295
	decreased circulating LDL cholesterol level	J:175295
	decreased circulating serum albumin level	J:175295
	decreased circulating total protein level	J:175295
	decreased total body fat amount	J:175295
	increased circulating fructosamine level	J:175295
Akap9^{tm1a(KOMP)Wtsi}/Akap9⁺ involves: C57BL/6 * C57BL/6N	abnormal pelvic girdle bone morphology	J:213427
	abnormal tooth morphology	J:213427
	decreased B cell number	J:213427
	decreased body weight	J:213427
	decreased circulating cholesterol level	J:213427
	decreased circulating glucose level	J:213427
	decreased circulating HDL cholesterol level	J:213427
	decreased circulating LDL cholesterol level	J:213427
	decreased circulating serum albumin level	J:213427
	decreased circulating total protein level	J:213427
	decreased lean body mass	J:213427
	decreased mature B cell number	J:213427
	decreased percent body fat/body weight	J:213427
	decreased total body fat amount	J:213427
	increased carbon dioxide production	J:213427
	increased CD4-positive, alpha-beta T cell number	J:213427
	increased CD8-positive, alpha-beta T cell number	J:213427
	increased circulating alkaline phosphatase level	J:213427
	increased energy expenditure	J:213427
	increased oxygen consumption	J:213427
	increased T cell number	J:213427
	lethality, incomplete penetrance	J:213427
Akap9^{tm1a(KOMP)Wtsi}/Akap9^{tm1a(KOMP)Wtsi} B6JTyr;B6N-Akap9^{tm1a(KOMP)Wtsi}/Wtsi	decreased body weight	J:175295
	decreased lumbar vertebrae number	J:175295
	preweaning lethality, incomplete penetrance	J:211773
Akap9^{tm1b(KOMP)Wtsi}/Akap9^{tm1b(KOMP)Wtsi} involves: C57BL/6 * C57BL/6N * FVB/N	male infertility	J:198499

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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