Clstn3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Clstn3
calsyntenin 3
MGI:2178323

30 phenotypes from 3 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Clstn3^tm1.1Amcr/Clstn3^tm1.1Amcr involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL	abnormal dentate gyrus morphology	J:201987
	abnormal excitatory postsynaptic potential	J:201987
	abnormal hippocampus CA1 region morphology	J:201987
	abnormal hippocampus pyramidal cell layer	J:201987
	abnormal hippocampus stratum radiatum morphology	J:201987
	decreased miniature excitatory postsynaptic current frequency	J:201987
	decreased miniature inhibitory postsynaptic current frequency	J:201987
Clstn3^{tm1b(EUCOMM)Hmgu}/Clstn3^{tm1b(EUCOMM)Hmgu} C57BL/6N-Clstn3^{tm1b(EUCOMM)Hmgu}/Cnrm	abnormal gait	J:211773
	abnormal lung morphology	J:211773
	decreased spleen weight	J:211773
	increased kidney weight	J:211773
	tremors	J:211773
Clstn3^{tm1b(EUCOMM)Hmgu}/Clstn3^{tm1b(EUCOMM)Hmgu} involves: BALB/cJ * C57BL/6N	normal behavior/neurological phenotype	J:293885
	decreased body mass index	J:293885
	decreased bone marrow adipose tissue amount	J:293885
	decreased brown adipose tissue amount	J:293885
	decreased brown fat cell size	J:293885
	decreased circulating glucose level	J:293885
	decreased compact bone mass	J:293885
	decreased susceptibility to diet-induced obesity	J:293885
	decreased white adipose tissue amount	J:293885
	decreased white fat cell size	J:293885
	increased carbon dioxide production	J:293885
	increased energy expenditure	J:293885
	increased insulin sensitivity	J:293885
	increased oxygen consumption	J:293885
	increased response to leptin	J:293885
	normal limbs/digits/tail phenotype	J:293885
	short femur	J:293885
Clstn3^{tm1c(EUCOMM)Hmgu}/Clstn3^{tm1c(EUCOMM)Hmgu} Lyz2^tm1(cre)Ifo/Lyz2⁺ involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * SJL	normal limbs/digits/tail phenotype	J:293885
Clstn3^{tm1c(EUCOMM)Hmgu}/Clstn3^{tm1c(EUCOMM)Hmgu} Tg(BGLAP-cre)1Clem/0 involves: C57BL/6 * C57BL/6N * FVB/NJ * SJL	normal limbs/digits/tail phenotype	J:293885
Clstn3^{tm1c(EUCOMM)Hmgu}/Clstn3^{tm1c(EUCOMM)Hmgu} Tg(Dbh-cre)KH212Gsat/0 involves: C57BL/6 * C57BL/6N * FVB/NTac * SJL	normal growth/size/body region phenotype	J:293885
	normal limbs/digits/tail phenotype	J:293885
Clstn3^{tm1c(EUCOMM)Hmgu}/Clstn3^{tm1c(EUCOMM)Hmgu} Tg(Syn1-cre)671Jxm/0 involves: C57BL/6 * C57BL/6N * CBA * SJL	decreased body mass index	J:293885
	decreased bone marrow adipose tissue amount	J:293885
	decreased compact bone mass	J:293885
	normal limbs/digits/tail phenotype	J:293885

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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