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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pfn3
profilin 3
MGI:2178800
26 phenotypes from 3 alleles in 1 genetic background
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Pfn3em1Hsc/Pfn3+
involves: C57BL/6 * DBA 		abnormal sperm head morphology J:320651
abnormal sperm nucleus morphology J:320651
oligozoospermia J:320651
normal reproductive system phenotype J:320651
Pfn3em1Hsc/Pfn3em1Hsc
involves: C57BL/6 * DBA 		abnormal acrosome assembly J:320651
abnormal acrosome morphology J:320651
abnormal Golgi apparatus morphology J:320651
abnormal Golgi vesicle transport J:320651
abnormal manchette assembly J:320651
abnormal proacrosomal vesicle fusion J:320651
abnormal protein level J:320651
abnormal sperm connecting piece morphology J:320651
abnormal sperm flagellum morphology J:320651
abnormal sperm head morphology J:320651
abnormal sperm midpiece morphology J:320651
abnormal sperm mitochondrial morphology J:320651
abnormal sperm mitochondrial sheath morphology J:320651
abnormal sperm nucleus morphology J:320651
abnormal spermiogenesis J:320651
asthenozoospermia J:320651
decreased litter size J:320651
decreased sperm progressive motility J:320651
detached acrosome J:320651
globozoospermia J:320651
impaired acrosome reaction J:320651
impaired autophagy J:320651
necrospermia J:320651
oligozoospermia J:320651
reduced male fertility J:320651
normal reproductive system phenotype J:320651
Pfn3em2Hsc/Pfn3+
involves: C57BL/6 * DBA 		abnormal sperm head morphology J:320651
abnormal sperm nucleus morphology J:320651
oligozoospermia J:320651
normal reproductive system phenotype J:320651
Pfn3em2Hsc/Pfn3em2Hsc
involves: C57BL/6 * DBA 		abnormal acrosome assembly J:320651
abnormal acrosome morphology J:320651
abnormal Golgi apparatus morphology J:320651
abnormal Golgi vesicle transport J:320651
abnormal manchette assembly J:320651
abnormal proacrosomal vesicle fusion J:320651
abnormal protein level J:320651
abnormal sperm connecting piece morphology J:320651
abnormal sperm flagellum morphology J:320651
abnormal sperm head morphology J:320651
abnormal sperm midpiece morphology J:320651
abnormal sperm mitochondrial morphology J:320651
abnormal sperm mitochondrial sheath morphology J:320651
abnormal sperm nucleus morphology J:320651
abnormal spermiogenesis J:320651
asthenozoospermia J:320651
decreased litter size J:320651
decreased sperm progressive motility J:320651
detached acrosome J:320651
globozoospermia J:320651
impaired acrosome reaction J:320651
impaired autophagy J:320651
necrospermia J:320651
oligozoospermia J:320651
reduced male fertility J:320651
normal reproductive system phenotype J:320651
Pfn3em3Hsc/Pfn3+
involves: C57BL/6 * DBA 		abnormal sperm head morphology J:320651
abnormal sperm nucleus morphology J:320651
oligozoospermia J:320651
normal reproductive system phenotype J:320651
Pfn3em3Hsc/Pfn3em3Hsc
involves: C57BL/6 * DBA 		abnormal acrosome assembly J:320651
abnormal acrosome morphology J:320651
abnormal Golgi apparatus morphology J:320651
abnormal Golgi vesicle transport J:320651
abnormal manchette assembly J:320651
abnormal proacrosomal vesicle fusion J:320651
abnormal protein level J:320651
abnormal sperm connecting piece morphology J:320651
abnormal sperm flagellum morphology J:320651
abnormal sperm head morphology J:320651
abnormal sperm midpiece morphology J:320651
abnormal sperm mitochondrial morphology J:320651
abnormal sperm mitochondrial sheath morphology J:320651
abnormal sperm nucleus morphology J:320651
abnormal spermiogenesis J:320651
asthenozoospermia J:320651
decreased litter size J:320651
decreased sperm progressive motility J:320651
detached acrosome J:320651
globozoospermia J:320651
impaired acrosome reaction J:320651
impaired autophagy J:320651
necrospermia J:320651
oligozoospermia J:320651
reduced male fertility J:320651
normal reproductive system phenotype J:320651
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
07/05/2024
MGI 6.24 		The Jackson Laboratory