Plxna4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Plxna4
plexin A4
MGI:2179061

34 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Plxna4^em1(IMPC)Mbp/Plxna4^em1(IMPC)Mbp C57BL/6NCrl-Plxna4^em1(IMPC)Mbp/MbpMmucd	abnormal cholesterol homeostasis	J:211773
	abnormal liver morphology	J:211773
	abnormal optic disk morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal testis morphology	J:211773
	abnormal vitreous body morphology	J:211773
	cataract	J:211773
	decreased body length	J:211773
	enlarged testis	J:211773
	hyperactivity	J:211773
	impaired pupillary reflex	J:211773
	increased exploration in new environment	J:211773
	persistence of hyaloid vascular system	J:211773
	small liver	J:211773
	small spleen	J:211773
Plxna4^tm1Hfu/Plxna4⁺ B6.Cg-Plxna4^tm1Hfu	abnormal anterior commissure morphology	J:98330
	abnormal anterior commissure pars anterior morphology	J:98330
	abnormal anterior commissure pars posterior morphology	J:98330
	abnormal axon guidance	J:98330
	abnormal cranial nerve morphology	J:98330
	abnormal spinal nerve morphology	J:98330
Plxna4^tm1Hfu/Plxna4^tm1Hfu B6.Cg-Plxna4^tm1Hfu	abnormal anterior commissure morphology	J:98330
	abnormal anterior commissure pars anterior morphology	J:98330
	abnormal anterior commissure pars posterior morphology	J:98330
	abnormal axon guidance	J:98330
	abnormal facial nerve morphology	J:98330
	abnormal glossopharyngeal nerve morphology	J:98330
	abnormal sensory neuron innervation pattern	J:98330
	abnormal spinal nerve morphology	J:98330
	abnormal sympathetic postganglionic fiber morphology	J:98330
	abnormal trigeminal nerve morphology	J:98330
	abnormal vagus nerve morphology	J:98330
	disorganized barrel cortex	J:98330
Plxna4^tm1Hfu/Plxna4^tm1Hfu involves: C57BL/6 * CBA	abnormal hippocampal mossy fiber morphology	J:135421, J:160509
Plxna4^tm1Hfu/Plxna4^tm1Hfu involves: C57BL/6 * CBA	abnormal neuron differentiation	J:135421
Plxna4^tm1Matl/Plxna4^tm1Matl either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * CD-1)	abnormal axon guidance	J:98440
	abnormal sensory neuron innervation pattern	J:98440
	abnormal trigeminal nerve morphology	J:98440
	decreased anterior commissure size	J:98440
Plxna4^tm1Matl/Plxna4^tm1Matl involves: 129P2/OlaHsd	abnormal amacrine cell morphology	J:172268
	abnormal neurite morphology	J:172268
	abnormal retina ganglion cell morphology	J:172268

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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