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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Plaat3
phospholipase A and acyltransferase 3
MGI:2179715
34 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Plaat3em1(IMPC)Tcp/Plaat3em1(IMPC)Tcp
C57BL/6NCrl-Plaat3em1(IMPC)Tcp/Tcp 		abnormal spleen morphology J:211773
impaired glucose tolerance J:211773
increased heart weight J:211773
increased mean corpuscular hemoglobin J:211773
Plaat3tm1.1Hsul/Plaat3tm1.1Hsul
B6.129P2-Pla2g16tm1.1Hsul 		abnormal glucose homeostasis J:239202
abnormal glycogen homeostasis J:239202
abnormal lipid metabolism J:239202
normal adipose tissue phenotype J:239202
decreased cellular glucose uptake J:239202
decreased circulating adiponectin level J:239202
decreased circulating free fatty acids level J:239202
decreased circulating leptin level J:239202
decreased circulating triglyceride level J:239202
decreased epididymal fat pad weight J:239202
decreased inguinal fat pad weight J:239202
decreased liver triglyceride level J:239202
decreased phospholipase A2 level J:239202
decreased renal fat pad weight J:239202
decreased susceptibility to diet-induced obesity J:239202
decreased susceptibility to weight gain J:239202
decreased triglyceride level J:239202
decreased white fat cell size J:239202
enhanced lipolysis J:239202
enlarged liver J:239202
hepatic steatosis J:239202
increased circulating alanine transaminase level J:239202
increased circulating glucose level J:239202
increased circulating insulin level J:239202
increased fasting circulating glucose level J:239202
increased fatty acid oxidation J:239202
increased lean body mass J:239202
increased oxygen consumption J:239202
insulin resistance J:239202
pale liver J:239202
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/17/2024
MGI 6.24 		The Jackson Laboratory