Casc3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Casc3
exon junction complex subunit
MGI:2179723

21 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Casc3^{Gt(RRU345)Byg}/Casc3⁺ involves: 129P2/OlaHsd * C57BL/6J	no abnormal phenotype detected	J:240595
Casc3^{Gt(RRU345)Byg}/Casc3^{Gt(RRU345)Byg} involves: 129P2/OlaHsd * C57BL/6J	decreased fetal size	J:240595
	delayed limb development	J:240595
	fetal growth retardation	J:240595
	lethality during fetal growth through weaning, complete penetrance	J:240595
	normal nervous system phenotype	J:240595
Casc3^{Gt(RRU345)Byg}/Casc3^{tm1(KOMP)Vlcg} involves: 129P2/OlaHsd * C57BL/6J * C57BL/6NTac	decreased fetal size	J:240595
	delayed limb development	J:240595
	fetal growth retardation	J:240595
	normal nervous system phenotype	J:240595
Casc3^{tm1(KOMP)Vlcg}/Casc3⁺ involves: C57BL/6J * C57BL/6NTac	no abnormal phenotype detected	J:240595
Casc3^{tm1(KOMP)Vlcg}/Casc3^{tm1(KOMP)Vlcg} involves: C57BL/6J * C57BL/6NTac	abnormal embryo morphology	J:240595
	decreased embryo size	J:240595
	embryonic growth retardation	J:240595
	embryonic lethality during organogenesis, complete penetrance	J:240595
Casc3^{tm1.1(KOMP)Vlcg}/Casc3⁺ C57BL/6NCrl-Casc3^{tm1.1(KOMP)Vlcg}/MbpMmucd	abnormal epididymis morphology	J:211773
	abnormal heart morphology	J:211773
	decreased blood urea nitrogen level	J:211773
	enlarged epididymis	J:211773
	enlarged heart	J:211773
Casc3^{tm1.1(KOMP)Vlcg}/Casc3^{tm1.1(KOMP)Vlcg} C57BL/6N-Casc3^{tm1.1(KOMP)Vlcg}/MbpMmucd	absent head fold	J:279207
	absent primitive node	J:279207
	decreased embryo size	J:279207
	embryonic lethality between implantation and placentation, complete penetrance	J:279207
	failure to gastrulate	J:279207
Casc3^{tm1.1(KOMP)Vlcg}/Casc3^{tm1.1(KOMP)Vlcg} C57BL/6NCrl-Casc3^{tm1.1(KOMP)Vlcg}/MbpMmucd	preweaning lethality, complete penetrance	J:211773
	preweaning lethality, incomplete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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