Mchr1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mchr1
melanin-concentrating hormone receptor 1
MGI:2180756

36 phenotypes from 8 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mchr1^M1Btlr/Mchr1^M1Btlr C57BL/6J-Mchr1^M1Btlr	decreased body weight	J:272868
Mchr1^tm1.1Blak/Mchr1^tm1.1Blak involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * FVB/N	abnormal frequency of paradoxical sleep	J:133199
	abnormal sleep pattern	J:133199
	impaired behavioral response to xenobiotic	J:133199
Mchr1^tm1Blak/Mchr1^tm1Blak involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal nervous system electrophysiology	J:101206
	abnormal passive avoidance behavior	J:101206
	decreased susceptibility to diet-induced obesity	J:101206
Mchr1^tm1Dgam/Mchr1⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	decreased body weight	J:95740
Mchr1^tm1Dgam/Mchr1^tm1Dgam involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal circadian temperature homeostasis	J:95740
	abnormal energy expenditure	J:95740
	decreased body weight	J:95740
	decreased susceptibility to diet-induced obesity	J:95740
	decreased total body fat amount	J:95740
	increased heart rate	J:95740
	increased locomotor activity	J:95740
	polyphagia	J:95740
Mchr1^tm1Lex/Mchr1^tm1Lex involves: 129S5/SvEvBrd * C57BL/6J	abnormal social investigation	J:136869
	decreased anxiety-related response	J:136869
	decreased percent body fat/body weight	J:185494
	decreased response to stress-induced hyperthermia	J:136869
	decreased serotonin level	J:136869
	increased body temperature	J:136869
Mchr1^tm1Ohl/Mchr1^tm1Ohl involves: 129S1/Sv * 129X1/SvJ * C57BL/6	decreased compact bone mass	J:90102
	decreased compact bone thickness	J:90102
	increased circulating type I collagen C-terminal telopeptide level	J:90102
	osteoporosis	J:90102
Mchr1^tm1Sqn/Mchr1^tm1Sqn involves: 129S7/SvEvBrd * C57BL/6	abnormal hormone level	J:81787
	abnormal metabolism	J:81787
	decreased circulating leptin level	J:81787
	decreased percent body fat/body weight	J:81787
	decreased respiratory quotient	J:81787
	decreased susceptibility to diet-induced obesity	J:81787
	decreased thyroxine level	J:81787
	normal homeostasis/metabolism phenotype	J:81787
	increased circulating corticosterone level	J:81787
	increased fluid intake	J:81787
	increased lean body mass	J:81787
	increased locomotor activity	J:81787
	polyphagia	J:81787
Mchr1^tm1Yush/Mchr1^tm1Yush involves: 129 * C57BL/6	abnormal energy expenditure	J:106819
	decreased circulating insulin level	J:106819
	decreased circulating leptin level	J:106819
	decreased susceptibility to diet-induced obesity	J:106819
	decreased total body fat amount	J:106819
	increased food intake	J:106819
	slow postnatal weight gain	J:106819
	weight loss	J:106819

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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