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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Slc5a2
solute carrier family 5 (sodium/glucose cotransporter), member 2
MGI:2181411
37 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Slc5a2m2Btlr/Slc5a2m2Btlr
C57BL/6J-Slc5a2m2Btlr 		increased body weight J:265117
increased susceptibility to induced colitis J:265117
increased tumor necrosis factor secretion J:265117
Slc5a2tm1Lex/Slc5a2tm1Lex
B6.129S5-Slc5a2tm1Lex 		abnormal renal filtration rate J:169917
abnormal renal glucose reabsorption J:169917
decreased circulating aldosterone level J:169917
decreased urine osmolality J:169917
increased fluid intake J:169917
increased food intake J:169917
increased renin activity J:169917
increased urine glucose level J:169917
polyuria J:169917
Slc5a2tm1Lex/Slc5a2tm1Lex
involves: 129S5/SvEvBrd * C57BL/6J 		abnormal bladder urine volume J:195941
abnormal blood homeostasis J:195941
abnormal circulating glucose level J:195941
abnormal urine homeostasis J:195941
normal adipose tissue phenotype J:195941
normal behavior/neurological phenotype J:195941
decreased body weight J:195941
decreased circulating glucose level J:195941
decreased circulating insulin level J:195941
decreased circulating phosphate level J:195941
decreased susceptibility to autoimmune diabetes J:195941
decreased total body fat amount J:195941
normal growth/size/body region phenotype J:195941
improved glucose tolerance J:195941
increased bone mineral density J:195941
increased bone trabecula number J:195941
increased circulating chloride level J:195941
increased circulating sodium level J:195941
increased food intake J:195941
increased urine chloride ion level J:195941
increased urine creatinine level J:195941
increased urine glucose level J:195941
increased urine magnesium level J:195941
increased urine phosphate level J:195941
increased urine potassium level J:195941
increased urine sodium level J:195941
increased urine urea nitrogen level J:195941
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory