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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Bbc3
BCL2 binding component 3
MGI:2181667
16 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Bbc3tm1Ast/Bbc3tm1Ast
C57BL/6-Bbc3tm1Ast 		decreased cellular sensitivity to gamma-irradiation J:86466
decreased sensitivity to induced cell death J:86466
Bbc3tm1Ast/Bbc3tm1Ast
involves: C57BL/6 * NZB 		abnormal CD8-positive, alpha-beta T cell physiology J:132819
abnormal neuron physiology J:127640, J:130581
abnormal splenic cell ratio J:132819
normal immune system phenotype J:132819
increased CD8-positive, alpha-beta T cell number J:132819
increased leukocyte cell number J:132819
Bbc3tm1Gpz/Bbc3tm1Gpz
involves: 129P2/OlaHsd 		abnormal cell death J:115660
abnormal heart left ventricle pressure J:116287
abnormal nervous system physiology J:115660
decreased apoptosis J:116287
decreased cellular sensitivity to gamma-irradiation J:115660
decreased lactate dehydrogenase level J:116287
decreased myocardial infarct size J:116287
normal hematopoietic system phenotype J:141545
increased left ventricle developed pressure J:116287
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory