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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Hps6
HPS6, biogenesis of lysosomal organelles complex 2 subunit 3
MGI:2181763
21 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
a/a
Hps6ru-5J/Hps6ru-5J
Lystbg/Lystbg
involves: C3H/Rl * C57BL/6J 		abnormal coat/hair pigmentation J:26546
abnormal eye pigmentation J:26546
decreased eye pigmentation J:26546
diluted coat color J:26546
a/a
Hps6ru/Hps6ru
B6.Cg-Hps6ru 		abnormal coat/hair pigmentation J:6064
abnormal kidney physiology J:6422
abnormal lateral geniculate nucleus morphology J:6064
abnormal retina ganglion cell morphology J:6064
decreased platelet ADP level J:7327
decreased platelet ATP level J:7327
decreased platelet dense granule number J:7327
decreased platelet serotonin level J:7327, J:29748
decreased susceptibility to atherosclerosis J:29748
increased bleeding time J:7327
a/a
Hps6ru/Hps6ru
involves: C57BL/6J 		abnormal eye pigmentation J:5346
abnormal melanogenesis J:5346
abnormal melanosome morphology J:5346
a/a
Hps6ru/Hps6ru
Not Specified 		abnormal choroid pigmentation J:81444
abnormal eye pigmentation J:13122, J:81444
abnormal iris pigmentation J:13122
decreased eye pigmentation J:13122
diluted coat color J:13122
hypopigmentation J:12970
A/A
Hps6ru/Hps6ru
Not Specified 		diluted coat color J:13122
a/a
Hps6ru/Hps6ru
Lystbg/Lystbg
involves: C3H/Rl * C57BL/6J 		abnormal melanogenesis J:5346
abnormal melanosome morphology J:5346
abnormal retina melanin granule morphology J:5346
a/a
Mregdsu/Mregdsu
Hps6ru/Hps6ru
involves: C57BL/6J 		diluted coat color J:29467
phenotypic reversion J:29467
Espnje/?
f/f
Hps6ru/Hps6ru
JE/LeJ 		abnormal mast cell degranulation J:37255
Hps6ru/Hps6ru
Lystbg-slt/Lystbg-slt
involves: YZ57/Ch 		decreased eye pigmentation J:25388
diluted coat color J:25388
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory