Acer1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Acer1
alkaline ceramidase 1
MGI:2181962

56 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Acer1^{tm1(KOMP)Vlcg}/Acer1^{tm1(KOMP)Vlcg} C57BL/6-Acer1^{tm1(KOMP)Vlcg}	abnormal enzyme/coenzyme activity	J:252017
	abnormal hair cycle	J:252017
	abnormal hair cycle anagen phase	J:252017
	abnormal hair cycle telogen phase	J:252017
	abnormal hair follicle physiology	J:252017
	abnormal piliary canal morphology	J:252017
	abnormal sebaceous lipid secretion	J:252017
	abnormal skin development	J:252017
	abnormal skin physiology	J:252017
	alopecia	J:252017
	dilated hair follicle infundibulum	J:252017
	normal mortality/aging	J:252017
	sebaceous gland hypertrophy	J:252017
	weight loss	J:252017
Acer1^{tm1a(EUCOMM)Wtsi}/Acer1^{tm1a(EUCOMM)Wtsi} C57BL/6N-A^tm1Brd Acer1^{tm1a(EUCOMM)Wtsi}/WtsiH	abnormal hair growth	J:211773
	abnormal retina morphology	J:211773
Acer1^{tm1a(EUCOMM)Wtsi}/Acer1^{tm1a(EUCOMM)Wtsi} C57BL/6N-Acer1^{tm1a(EUCOMM)Wtsi}	abnormal awl hair morphology	J:235775
	abnormal ceramide level	J:235775
	abnormal coat/ hair morphology	J:235775
	abnormal epidermis stratum corneum morphology	J:235775
	abnormal epidermis stratum granulosum morphology	J:235775
	abnormal hair cuticle	J:235775
	abnormal hair follicle bulge morphology	J:235775
	abnormal hair follicle development	J:235775
	abnormal hair follicle infundibulum morphology	J:235775
	abnormal hair follicle morphology	J:235775
	abnormal hair growth	J:235775
	abnormal hair shaft morphology	J:235775
	abnormal keratohyalin granule morphology	J:235775
	abnormal lipid level	J:235775
	abnormal sebocyte morphology	J:235775
	abnormal skin sebaceous gland morphology	J:235775
	abnormal sphingomyelin level	J:235775
	abnormal zigzag hair morphology	J:235775
	alopecia	J:235775
	decreased body weight	J:235775
	decreased brown adipose tissue mass	J:235775
	decreased brown fat cell lipid droplet size	J:235775
	decreased epididymal fat pad weight	J:235775
	decreased inguinal fat pad weight	J:235775
	decreased sphingosine level	J:235775
	delayed skin barrier formation	J:235775
	dilated hair follicle infundibulum	J:235775
	dry skin	J:235775
	enlarged sebaceous gland	J:235775
	epidermal hyperplasia	J:235775
	hyperactivity	J:235775
	hyperkeratosis	J:235775
	impaired skin barrier function	J:235775
	increased apoptosis	J:235775
	increased basal metabolism	J:235775
	increased energy expenditure	J:235775
	increased eosinophil cell number	J:235775
	increased epididymal fat pad weight	J:235775
	increased food intake	J:235775
	increased keratinocyte proliferation	J:235775
	scaly skin	J:235775
	skin inflammation	J:235775
	thick dermal layer	J:235775

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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