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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Usp7
ubiquitin specific peptidase 7
MGI:2182061
17 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Usp7tm1Wgu/Usp7tm1Wgu
involves: 129 * C57BL/6J 		absent proamniotic cavity J:168184
decreased embryo size J:168184
embryonic growth arrest J:168184
embryonic lethality between implantation and placentation, complete penetrance J:168184
Usp7tm2.1Wgu/Usp7tm2.1Wgu
involves: 129S6/SvEvTac * C57BL/6J 		abnormal embryo development J:203102
embryonic lethality, complete penetrance J:203102
Usp7tm2Wgu/Usp7tm2Wgu
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL 		normal mortality/aging J:203102
Usp7tm2Wgu/Usp7tm2Wgu
Tg(Nes-cre)1Kln/0
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL 		abnormal forebrain morphology J:203102
abnormal motor capabilities/coordination/movement J:203102
absent cerebellum J:203102
absent gastric milk in neonates J:203102
decreased brain size J:203102
decreased forebrain size J:203102
decreased neuron number J:203102
enlarged third ventricle J:203102
neonatal lethality, complete penetrance J:203102
thickened cerebral cortex J:203102
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory