Vrk3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Vrk3
vaccinia related kinase 3
MGI:2182465

26 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Vrk3^em1(IMPC)Mbp/Vrk3^em1(IMPC)Mbp C57BL/6NCrl-Vrk3^em1(IMPC)Mbp/Mmucd	abnormal eye morphology	J:211773
	abnormal kidney morphology	J:211773
	abnormal liver morphology	J:211773
	abnormal pancreas morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	enlarged kidney	J:211773
	enlarged spleen	J:211773
	scaly skin	J:211773
Vrk3^{Gt(YTA189)Byg}/Vrk3^{Gt(YTA189)Byg} B6.129P2-Vrk3^{Gt(YTA189)Byg}	abnormal AMPA-mediated synaptic currents	J:249352
	abnormal fear/anxiety-related behavior	J:249352
	abnormal hippocampal pyramidal neuron dendrite morphology	J:249352
	abnormal long-term spatial reference memory	J:249352
	abnormal nest building behavior	J:249352
	abnormal postsynaptic density morphology	J:249352
	abnormal pup retrieval	J:249352
	abnormal response to novel object	J:249352
	abnormal response to social novelty	J:249352
	abnormal social investigation	J:249352
	abnormal social/conspecific interaction behavior	J:249352
	decreased anxiety-related response	J:249352
	decreased dendritic spine density	J:249352
	impaired passive avoidance behavior	J:249352
	increased dendritic spine length	J:249352
	increased grooming behavior	J:249352
	increased locomotor activity	J:249352

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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