About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Grhl2
grainyhead like transcription factor 2
MGI:2182543
50 phenotypes from 7 alleles in 7 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Grhl2clft3/Grhl2clft3
involves: A/J * FVB/N 		decreased brain size J:174027
encephalomeningocele J:174027
midline facial cleft J:174027
Grhl2em1(IMPC)Mbp/Grhl2+
C57BL/6N-Grhl2em1(IMPC)Mbp/MbpMmucd 		abnormal blood vessel morphology J:211773
abnormal placenta morphology J:211773
increased freezing behavior J:211773
increased startle reflex J:211773
Grhl2em1(IMPC)Mbp/Grhl2em1(IMPC)Mbp
C57BL/6N-Grhl2em1(IMPC)Mbp/MbpMmucd 		abnormal abdominal wall morphology J:211773
abnormal craniofacial morphology J:211773
abnormal forebrain development J:211773
abnormal head shape J:211773
abnormal heart morphology J:211773
abnormal hindbrain development J:211773
abnormal limb morphology J:211773
abnormal midbrain development J:211773
abnormal neural tube closure J:211773
abnormal neural tube morphology J:211773
abnormal optic vesicle formation J:211773
abnormal pericardium morphology J:211773
abnormal placenta morphology J:211773
abnormal placenta size J:211773
embryonic growth retardation J:211773
exencephaly J:211773
preweaning lethality, complete penetrance J:211773
syndactyly J:211773
Grhl2Gt(AC0205)Wtsi/Grhl2+
involves: 129P2/OlaHsd * C57BL/6 		exencephaly J:170759
facial cleft J:170759
incomplete rostral neuropore closure J:170759
Grhl2Gt(AC0205)Wtsi/Grhl2Gt(AC0205)Wtsi
involves: 129P2/OlaHsd * BALB/c * C57BL/6 		abnormal neural tube closure J:170759
embryonic lethality during organogenesis, complete penetrance J:170759
exencephaly J:170759
facial cleft J:170759
incomplete rostral neuropore closure J:170759
spina bifida J:170759
Grhl2Gt(AC0205)Wtsi/Grhl2Gt(AC0205)Wtsi
involves: 129P2/OlaHsd * C57BL/6 		embryonic lethality during organogenesis, complete penetrance J:170759
Grhl2Gt(E115B04)Wrst/Grhl2Gt(E115B04)Wrst
involves: 129P2/OlaHsd * C57BL/6 		abnormal neural fold elevation formation J:167065
curly tail J:167065
embryonic growth retardation J:167065
embryonic lethality during organogenesis, complete penetrance J:167065
everted embryonic neuroepithelium J:167065
exencephaly J:167065
facial cleft J:167065
incomplete caudal neuropore closure J:167065
incomplete rostral neuropore closure J:167065
spina bifida J:167065
Grhl2Gt(RRU622)Byg/Grhl2Gt(RRU622)Byg
involves: 129P2/OlaHsd * C57BL/6 		abnormal neural fold elevation formation J:167065
curly tail J:167065
embryonic growth retardation J:167065
embryonic lethality during organogenesis, complete penetrance J:167065
everted embryonic neuroepithelium J:167065
exencephaly J:167065
facial cleft J:167065
incomplete caudal neuropore closure J:167065
incomplete rostral neuropore closure J:167065
spina bifida J:167065
Grhl2m1Nisw/Grhl2m1Nisw
129S1.B6-Grhl2m1Nisw 		abnormal heart morphology J:169829
abnormal heart ventricle morphology J:169829
abnormal respiratory conducting tube morphology J:169829
decreased embryo size J:169829
decreased litter size J:169829
embryonic growth retardation J:169829
embryonic lethality during organogenesis, incomplete penetrance J:169829
exencephaly J:169829
facial cleft J:169829
lethality, incomplete penetrance J:169829
open neural tube J:169829
small lung lobe J:169829
thin ventricular wall J:169829
thoracoabdominoschisis J:169829
Grhl2m1Nisw/Grhl2m1Nisw
involves: C3HeB/FeJ * C57BL/6J 		abnormal body wall morphology J:169829
abnormal cranium morphology J:169829
abnormal midface morphology J:169829
coloboma J:169829
exencephaly J:169829
facial cleft J:169829
interdigital webbing J:169829
lethality throughout fetal growth and development, complete penetrance J:169829
lethality, incomplete penetrance J:169829
open neural tube J:169829
split sternum J:169829
syndactyly J:169829
Grhl2tm1.1Jane/Grhl2tm1.1Jane
involves: 129S1/Sv * BALB/cJ * C57BL/6 		abnormal neural fold elevation formation J:164805
cranioschisis J:164805
embryonic lethality during organogenesis, complete penetrance J:164805
facial cleft J:164805
incomplete caudal neuropore closure J:164805
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory