Adgrf5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Adgrf5
adhesion G protein-coupled receptor F5
MGI:2182928

40 phenotypes from 6 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Adgrf5^m1Btlr/Adgrf5^m1Btlr C57BL/6J-Adgrf5^m1Btlr	increased circulating glucose level	J:225045
Adgrf5^tm1.1Bstc/Adgrf5^tm1.2Bstc Commd10^{Tg(Vav1-icre)A2Kio}/Commd10⁺ involves: 129S4/SvJae * C57BL/6J * C57BL/10 * CBA/Ca	normal respiratory system phenotype	J:196943
Adgrf5^tm1.1Bstc/Adgrf5^tm1.2Bstc Tg(Sftpc-cre)1Blh/0 involves: 129S4/SvJae * C57BL/6 * C57BL/6J * DBA/2	pulmonary alveolar proteinosis	J:196943
Adgrf5^tm1.1Bstc/Adgrf5^tm1.2Bstc Tg(SFTPC-rtTA)5Jaw/0 Tg(tetO-cre)1Jaw/0 involves: 129S4/SvJae * C57BL/6 * C57BL/6J	abnormal lipid level	J:196943
	increased cholesterol level	J:196943
	increased surfactant secretion	J:196943
Adgrf5^tm1.1Bstc/Adgrf5^tm1.2Bstc Tg(Tek-cre)12Flv/0 involves: 129S4/SvJae * C3H * C57BL/6 * C57BL/6J	normal respiratory system phenotype	J:196943
Adgrf5^tm1.2Bstc/Adgrf5^tm1.2Bstc involves: 129S4/SvJae * C57BL/6J	abnormal phospholipid level	J:196943
	abnormal surfactant physiology	J:196943
	abnormal type II pneumocyte morphology	J:196943
	decreased body weight	J:196943
	increased alveolar lamellar body number	J:196943
	increased lung cholesterol level	J:196943
	increased macrophage derived foam cell number	J:196943
	increased surfactant secretion	J:196943
	premature death	J:196943
	pulmonary alveolar proteinosis	J:196943
	respiratory distress	J:196943
Adgrf5^tm1.2Jpbs/Adgrf5^tm1.2Jpbs BALB/c-Adgrf5^tm1.2Jpbs	abnormal alveolar macrophage morphology	J:221769
	abnormal lung morphology	J:221769
	abnormal pulmonary alveolus morphology	J:221769
	abnormal respiration	J:221769
	abnormal respiratory system physiology	J:221769
	abnormal surfactant composition	J:221769
	abnormal surfactant physiology	J:221769
	normal growth/size/body region phenotype	J:221769
	increased surfactant secretion	J:221769
	respiratory distress	J:221769
	tachypnea	J:221769
Adgrf5^{tm1b(KOMP)Wtsi}/Adgrf5^{tm1b(KOMP)Wtsi} C57BL/6N-Adgrf5^{tm1b(KOMP)Wtsi}/Tcp	decreased bone mineral content	J:211773
	decreased bone mineral density	J:211773
	decreased circulating cholesterol level	J:211773
	decreased hematocrit	J:211773
	decreased hemoglobin content	J:211773
	decreased leukocyte cell number	J:211773
	decreased lymphocyte cell number	J:211773
	decreased mean corpuscular hemoglobin	J:211773
	decreased mean corpuscular volume	J:211773
	decreased monocyte cell number	J:211773
	impaired glucose tolerance	J:211773
	increased grip strength	J:211773
	increased red blood cell distribution width	J:211773
Adgrf5^tm1Shiro/Adgrf5^tm1Shiro B6.Cg-Adgrf5^tm1Shiro	abnormal alveolar macrophage morphology	J:204701
	abnormal pulmonary alveolus morphology	J:204701
	emphysema	J:204701
	increased lung weight	J:204701
	increased macrophage cell number	J:204701
	increased surfactant secretion	J:204701
	increased type II pneumocyte number	J:204701

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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