Pkhd1l1 Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pkhd1l1
polycystic kidney and hepatic disease 1-like 1
MGI:2183153

12 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pkhd1l1^em1(IMPC)H/Pkhd1l1^em1(IMPC)H C57BL/6N-Pkhd1l1^em1(IMPC)H/H	decreased lymphocyte cell number	J:211773
	increased leukocyte cell number	J:211773
	increased monocyte cell number	J:211773
	increased neutrophil cell number	J:211773
	increased red blood cell distribution width	J:211773
Pkhd1l1^{tm2c(EUCOMM)Hmgu}/Pkhd1l1^{tm2c(EUCOMM)Hmgu} Gfi1^tm1(cre)Gan/Gfi1⁺ involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6N	prenatal lethality, complete penetrance	J:280240
Pkhd1l1^{tm2c(EUCOMM)Hmgu}/Pkhd1l1^{tm2c(EUCOMM)Hmgu} Tg(Atoh1-cre)1Bfri/0 involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6N * CBA	abnormal distortion product otoacoustic emission	J:280240
	abnormal outer hair cell stereociliary bundle morphology	J:280240
	abnormal tectorial membrane morphology	J:280240
	decreased outer hair cell stereocilia number	J:280240
	impaired hearing	J:280240
	increased or absent threshold for auditory brainstem response	J:280240

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24