Pkhd1l1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pkhd1l1
polycystic kidney and hepatic disease 1-like 1
MGI:2183153

12 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pkhd1l1^em1(IMPC)H/Pkhd1l1^em1(IMPC)H C57BL/6N-Pkhd1l1^em1(IMPC)H/H	decreased lymphocyte cell number	J:211773
	increased leukocyte cell number	J:211773
	increased monocyte cell number	J:211773
	increased neutrophil cell number	J:211773
	increased red blood cell distribution width	J:211773
Pkhd1l1^{tm2c(EUCOMM)Hmgu}/Pkhd1l1^{tm2c(EUCOMM)Hmgu} Gfi1^tm1(cre)Gan/Gfi1⁺ involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6N	prenatal lethality, complete penetrance	J:280240
Pkhd1l1^{tm2c(EUCOMM)Hmgu}/Pkhd1l1^{tm2c(EUCOMM)Hmgu} Tg(Atoh1-cre)1Bfri/0 involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6N * CBA	abnormal distortion product otoacoustic emission	J:280240
	abnormal outer hair cell stereociliary bundle morphology	J:280240
	abnormal tectorial membrane morphology	J:280240
	decreased outer hair cell stereocilia number	J:280240
	impaired hearing	J:280240
	increased or absent threshold for auditory brainstem response	J:280240

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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