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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ash1l
ASH1 like histone lysine methyltransferase
MGI:2183158
50 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ash1lGt(AL0395)Wtsi/Ash1lGt(AL0395)Wtsi
involves: 129P2/OlaHsd * C57BL/6J 		abnormal cauda epididymis morphology J:227516
abnormal cornea epithelium morphology J:227516
abnormal decidualization J:227516
abnormal epididymis morphology J:227516
abnormal postimplantation uterine environment J:227516
abnormal sperm number J:227516
abnormal sternum morphology J:227516
abnormal uterus morphology J:227516
abnormal vas deferens morphology J:227516
absent Meibomian glands J:227516
asymmetric sternocostal joints J:227516
blepharitis J:227516
decreased abdominal adipose tissue amount J:227516
decreased body size J:227516
decreased body weight J:227516
decreased endometrial gland number J:227516
decreased sebaceous gland number J:227516
decreased survivor rate J:227516
female infertility J:227516
increased rib number J:227516
postnatal growth retardation J:227516
reduced male fertility J:227516
small uterus J:227516
thin endometrium J:227516
Ash1ltm2b(EUCOMM)Hmgu/Ash1l+
C57BL/6N-Ash1ltm2b(EUCOMM)Hmgu/Nju 		abnormal coat appearance J:211773
impaired pupillary reflex J:211773
increased basophil cell number J:211773
increased eosinophil cell number J:211773
increased fasting circulating glucose level J:211773
increased grip strength J:211773
increased heart weight J:211773
Ash1ltm2b(EUCOMM)Hmgu/Ash1ltm2b(EUCOMM)Hmgu
C57BL/6N-Ash1ltm2b(EUCOMM)Hmgu/Nju 		preweaning lethality, complete penetrance J:211773
Ash1lTn(pb-Act-RFP)1.AF0-180T25Zhu/Ash1lTn(pb-Act-RFP)1.AF0-180T25Zhu
B6.FVB-Ash1lTn(pb-Act-RFP)1.AF0-180T25Zhu 		glomerulonephritis J:208213
normal immune system phenotype J:208213
increased autoantibody level J:208213
increased circulating interleukin-6 level J:208213
increased circulating tumor necrosis factor level J:208213
increased IgA level J:208213
increased IgG1 level J:208213
increased IgG2a level J:208213
increased IgG2b level J:208213
increased IgM level J:208213
increased interleukin-6 secretion J:208213
increased susceptibility to autoimmune disorder J:208213
increased susceptibility to bacterial infection J:208213
increased susceptibility to bacterial infection induced morbidity/mortality J:208213
increased susceptibility to endotoxin shock J:208213
increased susceptibility to induced arthritis J:208213
increased tumor necrosis factor secretion J:208213
pulmonary hyperemia J:208213
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory