Fgd4 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fgd4
FYVE, RhoGEF and PH domain containing 4
MGI:2183747

9 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fgd4^tm1.1Ics/Fgd4^tm1.1Ics Not Specified	abnormal action potential	J:190437
	abnormal myelin sheath morphology	J:190437
	abnormal myelination	J:190437
	abnormal nervous system electrophysiology	J:190437
	decreased grip strength	J:190437
	decreased nerve conduction velocity	J:190437
	demyelination	J:190437
Fgd4^{tm1a(EUCOMM)Wtsi}/Fgd4^{tm1a(EUCOMM)Wtsi} C57BL/6N-Fgd4^{tm1a(EUCOMM)Wtsi}/Wtsi	increased circulating LDL cholesterol level	J:211773
Fgd4^tm1Ics/Fgd4^tm1Ics Mnx1^tm4(cre)Tmj/Mnx1⁺ involves: 129S1/Sv	normal nervous system phenotype	J:190437
Fgd4^tm1Ics/Fgd4^tm1Ics Tg(Dhh-cre)1Mejr/0 involves: FVB/N	abnormal myelination	J:190437
Fgd4^tm1Ics/Fgd4^tm1Ics Tg(Plp1-cre/ERT2)1Ueli/0 involves: C57BL/6 * DBA/2	abnormal myelin sheath morphology	J:190437

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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