Pdk3 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pdk3
pyruvate dehydrogenase kinase, isoenzyme 3
MGI:2384308

8 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Pdk1^{tm1a(EUCOMM)Hmgu}/Pdk1^{tm1a(EUCOMM)Hmgu} Pdk2^tm1Rhar/Pdk2^tm1Rhar Pdk3^em1Eze/Pdk3^em1Eze Pdk4^tm1Rhar/Pdk4^tm1Rhar involves: 129 * C57BL/6J * C57BL/6N	abnormal circulating protein level	J:303714
	decreased circulating glucose level	J:303714
	decreased circulating lactate level	J:303714
	increased circulating ketone body level	J:303714
	postnatal lethality, complete penetrance	J:303714
	normal skeleton phenotype	J:303714
Pdk1^{tm1c(EUCOMM)Hmgu}/Pdk1^{tm1c(EUCOMM)Hmgu} Pdk2^tm1Rhar/Pdk2^tm1Rhar Pdk3^em1Eze/Pdk3^em1Eze Pdk4^tm1Rhar/Pdk4^tm1Rhar Tg(Prrx1-cre)1Cjt/0 involves: 129 * C57BL/6J * C57BL/6N * SJL/J	normal mortality/aging	J:303714
	normal reproductive system phenotype	J:303714
	normal skeleton phenotype	J:303714

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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