Il27 Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Il27
interleukin 27
MGI:2384409

8 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Il27^{tm1b(EUCOMM)Wtsi}/Il27^{tm1b(EUCOMM)Wtsi} C57BL/6N-Il27^{tm1b(EUCOMM)Wtsi}/Wtsi	decreased CD4-positive, alpha-beta memory T cell number	J:211773
	increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number	J:211773
Il27^tm1Cua/Il27^tm1Cua C57BL/6-Il27^tm1Cua	abnormal CD4-positive T cell differentiation	J:147706
	increased susceptibility to experimental autoimmune encephalomyelitis	J:147706
	increased susceptibility to type IV hypersensitivity reaction	J:147706
Il27^tm1Lex/Il27^tm1Lex involves: 129S/SvEvBrd	increased circulating interleukin-12b level	J:187660
	increased interferon-gamma secretion	J:187660
	increased susceptibility to parasitic infection induced morbidity/mortality	J:187660

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/05/2024 MGI 6.24