Eif4g1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Eif4g1
eukaryotic translation initiation factor 4, gamma 1
MGI:2384784

21 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Eif4g1^{em1(IMPC)Hmgu}/Eif4g1⁺ C57BL/6NCrl-Eif4g1^{em1(IMPC)Hmgu}/Ieg	abnormal retina blood vessel morphology	J:211773
	abnormal retina vasculature morphology	J:211773
	abnormal vocalization	J:211773
	decreased bone mineral density	J:211773
	decreased lean body mass	J:211773
	decreased spleen weight	J:211773
	increased circulating alanine transaminase level	J:211773
	increased circulating aspartate transaminase level	J:211773
	increased circulating chloride level	J:211773
	increased fasting circulating glucose level	J:211773
	increased total body fat amount	J:211773
	increased total retina thickness	J:211773
Eif4g1^{em1(IMPC)Hmgu}/Eif4g1^{em1(IMPC)Hmgu} C57BL/6NCrl-Eif4g1^{em1(IMPC)Hmgu}/Ieg	preweaning lethality, complete penetrance	J:211773
Eif4g1^em1Bjbl/Eif4g1^em1Bjbl C57BL/6J-Eif4g1^em1Bjbl	abnormal response to social novelty	J:287743
	abnormal social investigation	J:287743
	normal behavior/neurological phenotype	J:287743
	enhanced long-term potentiation	J:287743
	normal hearing/vestibular/ear phenotype	J:287743
	impaired contextual conditioning behavior	J:287743
	increased miniature inhibitory postsynaptic current amplitude	J:287743
Eif4g1^tm1.1Mjff/Eif4g1^tm1.1Mjff involves: C57BL/6	no abnormal phenotype detected	J:101977

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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