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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Lpcat1
lysophosphatidylcholine acyltransferase 1
MGI:2384812
28 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Lpcat1Gt(BC0405)Wtsi/Lpcat1Gt(BC0405)Wtsi
involves: 129P2/OlaHsd * Black Swiss 		abnormal lung morphology J:161467
abnormal surfactant physiology J:161467
atelectasis J:161467
cyanosis J:161467
lung hemorrhage J:161467
neonatal lethality, complete penetrance J:161467
respiratory distress J:161467
Lpcat1rd11-2J/Lpcat1rd11-2J
B6.Cg-Lpcat1rd11-2J/BocJ 		abnormal cone electrophysiology J:163743
abnormal eye electrophysiology J:163743
abnormal ocular fundus morphology J:163743
abnormal phospholipid level J:163743
abnormal rod electrophysiology J:163743
retina cone cell degeneration J:163743
retina degeneration J:163743
retina photoreceptor degeneration J:163743
retina rod cell degeneration J:163743
Lpcat1rd11/Lpcat1rd11
B6.Cg-Lpcat1rd11/BocJ 		abnormal cone electrophysiology J:163743
abnormal electroretinogram waveform feature J:229509
abnormal eye electrophysiology J:163743, J:163976
abnormal ocular fundus morphology J:163743
abnormal phospholipid level J:163743
abnormal retina vasculature morphology J:163743
abnormal rod electrophysiology J:163743
abnormal vision J:229509
absent photoreceptor outer segment J:229509
decreased b-wave amplitude J:229509
decreased total retina thickness J:229509
retina cone cell degeneration J:163743
retina degeneration J:163976, J:229509
retina photoreceptor degeneration J:163743
retina rod cell degeneration J:163743
thin retina outer nuclear layer J:229509
thin retina outer plexiform layer J:229509
Lpcat1tm1b(EUCOMM)Hmgu/Lpcat1tm1b(EUCOMM)Hmgu
C57BL/6N-Lpcat1tm1b(EUCOMM)Hmgu/H 		abnormal retina morphology J:211773
abnormal retina vasculature morphology J:211773
hyperactivity J:211773
impaired pupillary reflex J:211773
mydriasis J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory