Lpcat1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lpcat1
lysophosphatidylcholine acyltransferase 1
MGI:2384812

28 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lpcat1^{Gt(BC0405)Wtsi}/Lpcat1^{Gt(BC0405)Wtsi} involves: 129P2/OlaHsd * Black Swiss	abnormal lung morphology	J:161467
	abnormal surfactant physiology	J:161467
	atelectasis	J:161467
	cyanosis	J:161467
	lung hemorrhage	J:161467
	neonatal lethality, complete penetrance	J:161467
	respiratory distress	J:161467
Lpcat1^rd11-2J/Lpcat1^rd11-2J B6.Cg-Lpcat1^rd11-2J/BocJ	abnormal cone electrophysiology	J:163743
	abnormal eye electrophysiology	J:163743
	abnormal ocular fundus morphology	J:163743
	abnormal phospholipid level	J:163743
	abnormal rod electrophysiology	J:163743
	retina cone cell degeneration	J:163743
	retina degeneration	J:163743
	retina photoreceptor degeneration	J:163743
	retina rod cell degeneration	J:163743
Lpcat1^rd11/Lpcat1^rd11 B6.Cg-Lpcat1^rd11/BocJ	abnormal cone electrophysiology	J:163743
	abnormal electroretinogram waveform feature	J:229509
	abnormal eye electrophysiology	J:163743, J:163976
	abnormal ocular fundus morphology	J:163743
	abnormal phospholipid level	J:163743
	abnormal retina vasculature morphology	J:163743
	abnormal rod electrophysiology	J:163743
	abnormal vision	J:229509
	absent photoreceptor outer segment	J:229509
	decreased b-wave amplitude	J:229509
	decreased total retina thickness	J:229509
	retina cone cell degeneration	J:163743
	retina degeneration	J:163976, J:229509
	retina photoreceptor degeneration	J:163743
	retina rod cell degeneration	J:163743
	thin retina outer nuclear layer	J:229509
	thin retina outer plexiform layer	J:229509
Lpcat1^{tm1b(EUCOMM)Hmgu}/Lpcat1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Lpcat1^{tm1b(EUCOMM)Hmgu}/H	abnormal retina morphology	J:211773
	abnormal retina vasculature morphology	J:211773
	hyperactivity	J:211773
	impaired pupillary reflex	J:211773
	mydriasis	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 08/02/2024 MGI 6.24