Cc2d1a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cc2d1a
coiled-coil and C2 domain containing 1A
MGI:2384831

23 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cc2d1a^tm1.1Thkn/Cc2d1a^tm1.1Thkn involves: 129S4/SvJae * C57BL/6 * SJL	no abnormal phenotype detected	J:236761
Cc2d1a^tm1.1Thkn/Cc2d1a^tm1.1Thkn Tg(Nes-cre)1Kln/0 involves: 129S4/SvJae * C57BL/6 * SJL	cyanosis	J:236761
	neonatal lethality, complete penetrance	J:236761
	respiratory distress	J:236761
Cc2d1a^tm1.1Thkn/Cc2d1a^tm1.1Thkn Tg(Vil1-cre)997Gum/0 involves: 129S4/SvJae * C57BL/6 * SJL	normal digestive/alimentary phenotype	J:236761
Cc2d1a^tm1.2Thkn/Cc2d1a^tm1.2Thkn involves: 129S4/SvJae * BALB/cJ * C57BL/6 * SJL	abnormal cell morphology	J:236761
	cyanosis	J:236761
	neonatal lethality, complete penetrance	J:236761
	respiratory distress	J:236761
Cc2d1a^{tm1a(KOMP)Wtsi}/Cc2d1a^{tm1a(KOMP)Wtsi} involves: C57BL/6J * C57BL/6N	decreased interferon-beta secretion	J:190401
	decreased interleukin-6 secretion	J:190401
Cc2d1a^tm1Bisu/Cc2d1a^tm1Bisu Not Specified	abnormal brain vasculature morphology	J:184920
	abnormal dendrite morphology	J:184920
	abnormal neuron physiology	J:184920
	decreased body weight	J:184920
	decreased CNS synapse formation	J:184920
	hunched posture	J:184920
	increased cellular sensitivity to hydrogen peroxide	J:184920
	neonatal lethality, incomplete penetrance	J:184920
	respiratory distress	J:184920
Cc2d1a^tm1Zjc/Cc2d1a^tm1Zjc involves: 129S/SvEv * C57BL/6	abnormal excitatory postsynaptic currents	J:177407
	abnormal inhibitory postsynaptic currents	J:177407
	abnormal miniature inhibitory postsynaptic current frequency	J:177407
	abnormal miniature inhibitory postsynaptic currents	J:177407
	abnormal synaptic vesicle recycling	J:177407
	increased miniature inhibitory postsynaptic current amplitude	J:177407
	perinatal lethality, complete penetrance	J:177407

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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