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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Slc39a14
solute carrier family 39 (zinc transporter), member 14
MGI:2384851
45 phenotypes from 4 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gt(ROSA)26Sortm1(CAG-Slc39a14*L438R)Wvh/Gt(ROSA)26Sor+
Tg(Ctsk-cre)1Rda/0
involves: C57BL/6 		abnormal compact bone morphology J:261326
abnormal tibia morphology J:261326
normal craniofacial phenotype J:261326
decreased bone ossification J:261326
decreased bone trabecular spacing J:261326
increased bone mineralization J:261326
increased bone trabecula number J:261326
increased trabecular bone thickness J:261326
increased trabecular bone volume J:261326
Gt(ROSA)26Sortm1(CAG-Slc39a14*L438R)Wvh/Gt(ROSA)26Sor+
Tg(Runx2-icre)1Jtuc/0
involves: FVB/N 		abnormal compact bone morphology J:261326
abnormal osteoblast physiology J:261326
normal craniofacial phenotype J:261326
decreased bone mineralization J:261326
decreased bone trabecula number J:261326
decreased diameter of femur J:261326
decreased diameter of tibia J:261326
decreased femur stiffness J:261326
decreased trabecular bone connectivity density J:261326
decreased trabecular bone mass J:261326
decreased trabecular bone volume J:261326
fragile skeleton J:261326
increased bone mineralization J:261326
increased bone ossification J:261326
increased bone trabecular spacing J:261326
increased femur compact bone thickness J:261326
increased osteoclast cell number J:261326
Slc39a14tm1b(NCOM)Mfgc/Slc39a14tm1b(NCOM)Mfgc
C57BL/6N-Slc39a14tm1b(NCOM)Mfgc/Tcp 		preweaning lethality, incomplete penetrance J:211773
Slc39a14tm1Lex/Slc39a14tm1Lex
B6;129S5-Slc39a14tm1Lex/Mmucd 		normal skeleton phenotype J:261326
Slc39a14tm1Lex/Slc39a14tm1Lex
involves: 129S5/SvEvBrd * C57BL/6J 		abnormal liver zinc level J:236296
decreased hepatocyte proliferation J:236296
decreased liver weight J:236296
impaired liver regeneration J:236296
increased circulating alanine transaminase level J:236296
Slc39a14tm1Thir/Slc39a14tm1Thir
involves: 129 * C57BL/6 		abnormal chondrocyte differentiation J:171670
abnormal gluconeogenesis J:171670
abnormal growth hormone level J:171670
abnormal liver zinc level J:171670
decreased body size J:171670
decreased body weight J:171670
decreased bone mineral density J:171670
decreased bone trabecula number J:171670
decreased bone volume J:171670
decreased circulating insulin-like growth factor I level J:171670
decreased length of long bones J:171670
increased bone trabecular spacing J:171670
osteoporosis J:171670
postnatal growth retardation J:171670
scoliosis J:171670
short femur J:171670
short tibia J:171670
torticollis J:171670
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory