Prdm9 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prdm9
PR domain containing 9
MGI:2384854

26 phenotypes from 6 alleles in 11 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prdm9^em2Kpgn/Prdm9⁺ C57BL/6J-Prdm9^em2Kpgn/Kpgn	decreased oocyte number	J:299008
Prdm9^em2Kpgn/Prdm9^em2Kpgn (C57BL/6J-Prdm9^em2Kpgn/Kpgn x WSB/EiJ)F2	decreased testis weight	J:299008
	male infertility	J:299008
Prdm9^em2Kpgn/Prdm9^em2Kpgn C57BL/6J-Prdm9^em2Kpgn/Kpgn	abnormal chiasmata formation	J:299008
	abnormal chromosomal synapsis	J:299008
	abnormal DNA methylation during gametogenesis	J:299008
	abnormal female meiosis	J:299008
	arrest of male meiosis	J:299008
	decreased oocyte number	J:299008
	male infertility	J:299008
	reduced female fertility	J:299008
	small ovary	J:299008
Prdm9^em3Kpgn/Prdm9^em3Kpgn involves: C57BL/6J	normal cellular phenotype	J:280261
Prdm9^M1045Lja/Prdm9⁺ involves: C57BL/6J * DBA	abnormal spermatid morphology	J:179895
	abnormal spermiogenesis	J:179895
	azoospermia	J:179895
	decreased male germ cell number	J:179895
	small testis	J:179895
Prdm9^M1045Lja/Prdm9^M1045Lja involves: C57BL/6J * DBA	abnormal germ cell morphology	J:179895
	azoospermia	J:179895
	decreased testis weight	J:179895
	small testis	J:179895
Prdm9^repro7/Prdm9^repro7 B6;C3Fe-Prdm9^repro7/J	abnormal seminiferous tubule morphology	J:92463
	absent ovarian follicles	J:92463
	arrest of male meiosis	J:92463
	azoospermia	J:92463
	decreased testis weight	J:92463
	female infertility	J:92463
	male infertility	J:92463
	small ovary	J:92463
Prdm9^tm1.1Kpgn/Prdm9^tm1.1Kpgn B6.Cg-Prdm9^tm1.1Kpgn	abnormal meiosis	J:222816
Prdm9^tm1Ymat/Prdm9^tm1Ymat B6.129P2-Prdm9^tm1Ymat	abnormal chiasmata formation	J:299008
	abnormal chromosomal synapsis	J:296124
	abnormal double-strand DNA break repair	J:296124
	abnormal female meiosis	J:299008
	abnormal female meiosis I arrest	J:299008
	female infertility	J:299008
	male infertility	J:296124
Prdm9^tm1Ymat/Prdm9^tm1Ymat B6.Cg-Prdm9^tm1Ymat	normal cellular phenotype	J:280261
Prdm9^tm1Ymat/Prdm9^tm1Ymat B6.Cg-Prdm9^tm1Ymat	normal reproductive system phenotype	J:280261
Prdm9^tm1Ymat/Prdm9^tm1Ymat C3.129P2(B6)-Prdm9^tm1Ymat/HandJ	abnormal female meiosis	J:299008
	arrest of male meiosis	J:299008
	decreased oocyte number	J:299008
	female infertility	J:299008
	male infertility	J:299008
Prdm9^tm1Ymat/Prdm9^tm1Ymat CAST.129P2(B6)-Prdm9^tm1Ymat/Hand	male infertility	J:299008
	normal reproductive system phenotype	J:299008
Prdm9^tm1Ymat/Prdm9^tm1Ymat involves: 129P2/OlaHsd * C57BL/6	abnormal chromosomal synapsis	J:102875
	abnormal double-strand DNA break repair	J:102875
	abnormal female meiosis	J:102875
	abnormal gametogenesis	J:102875
	abnormal ovarian folliculogenesis	J:102875
	arrest of male meiosis	J:102875
	azoospermia	J:102875
	decreased oocyte number	J:102875
	decreased testis weight	J:102875
	female infertility	J:102875
	male infertility	J:102875

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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