Micu1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Micu1
mitochondrial calcium uptake 1
MGI:2384909

24 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Micu1^em#Fink/Micu1^em#Fink C57BL/6N-Micu1^em#Fink	abnormal brain development	J:238984
	abnormal cerebellum development	J:238984
	abnormal mitochondrial morphology	J:238984
	abnormal mitochondrial physiology	J:238984
	abnormal muscle physiology	J:238984
	abnormal Purkinje cell dendrite morphology	J:238984
	ataxia	J:238984
	decreased B cell number	J:238984
	decreased birth body size	J:238984
	decreased follicular B cell number	J:238984
	decreased grip strength	J:238984
	decreased skeletal muscle fiber number	J:238984
	impaired coordination	J:238984
	increased B cell apoptosis	J:238984
	increased circulating lactate level	J:238984
	oxidative stress	J:238984
	postnatal lethality, incomplete penetrance	J:238984
Micu1^tm1bNarl/Micu1⁺ C57BL/6N-Micu1^tm1bNarl/Narl	increased total body fat amount	J:211773
Micu1^tm1bNarl/Micu1⁺ C57BL/6N-Micu1^tm1bNarl/Narl	long tibia	J:211773
Micu1^tm1bNarl/Micu1^tm1bNarl C57BL/6N-Micu1^tm1bNarl/Narl	abnormal gait	J:211773
	abnormal locomotor behavior	J:211773
	abnormal snout morphology	J:211773
	abnormal tail length	J:211773
	preweaning lethality, incomplete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/29/2024 MGI 6.24