Appl2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Appl2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
MGI:2384914

12 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Appl2^tm1.1Test/Appl2^tm1.1Test Not Specified	abnormal cell physiology	J:227340
	decreased fibroblast cell migration	J:227340
	decreased mean corpuscular hemoglobin concentration	J:227340
	normal hematopoietic system phenotype	J:227340
	increased hematocrit	J:227340
	increased mean corpuscular volume	J:227340
Appl2^tm1Smoc/Appl2^tm1Smoc Tg(Ckmm-cre)5Khn/0 involves: FVB	normal behavior/neurological phenotype	J:230004
	normal growth/size/body region phenotype	J:230004
	normal homeostasis/metabolism phenotype	J:230004
	improved glucose tolerance	J:230004
	increased insulin sensitivity	J:230004
	increased skeletal muscle cell glucose uptake	J:230004

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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