Fermt2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fermt2
fermitin family member 2
MGI:2385001

51 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fermt2^{Gt(AM0293)Wtsi}/Fermt2^{Gt(AM0293)Wtsi} involves: 129P2/OlaHsd * C57BL/6	embryonic lethality between implantation and somite formation, complete penetrance	J:147662
Fermt2^tm1.1Gxo/Fermt2⁺ B6.129(Cg)-Fermt2^tm1.1Gxo	no abnormal phenotype detected	J:224370
Fermt2^tm1.1Gxo/Fermt2⁺ Tg(Prrx1-cre)1Cjt/0 B6.Cg-Fermt2^tm1.1Gxo Tg(Prrx1-cre)1Cjt	no abnormal phenotype detected	J:224370
Fermt2^tm1.1Gxo/Fermt2^tm1.1Gxo B6.129(Cg)-Fermt2^tm1.1Gxo	no abnormal phenotype detected	J:224370
Fermt2^tm1.1Gxo/Fermt2^tm1.1Gxo Tg(Col2a1-cre)1Bhr/0 B6.Cg-Fermt2^tm1.1Gxo Tg(Col2a1-cre)1Bhr	abnormal long bone epiphyseal plate morphology	J:224370
	abnormal skeleton morphology	J:224370
	decreased body size	J:224370
	decreased bone mineral density	J:224370
	decreased femur compact bone thickness	J:224370
	decreased length of long bones	J:224370
	decreased trabecular bone volume	J:224370
	delayed endochondral bone ossification	J:224370
	kyphosis	J:224370
	postnatal growth retardation	J:224370
	premature death	J:224370
	respiratory distress	J:224370
	short limbs	J:224370
	normal skeleton phenotype	J:224370
	small thoracic cage	J:224370
	small vertebrae	J:224370
	vertebral compression	J:224370
Fermt2^tm1.1Gxo/Fermt2^tm1.1Gxo Tg(Prrx1-cre)1Cjt/0 B6.Cg-Fermt2^tm1.1Gxo Tg(Prrx1-cre)1Cjt	abnormal chondrocyte morphology	J:224370
	abnormal intramembranous bone ossification	J:224370
	abnormal limb development	J:224370
	abnormal long bone epiphyseal plate proliferative zone	J:224370
	abnormal long bone hypertrophic chondrocyte zone	J:224370
	abnormal scapula morphology	J:224370
	abnormal skeleton morphology	J:224370
	abnormal sternum morphology	J:224370
	absent neurocranium	J:224370
	brachydactyly	J:224370
	brachyphalangia	J:224370
	chondrodystrophy	J:224370
	clavicle hypoplasia	J:224370
	decreased chondrocyte number	J:224370
	decreased chondrocyte proliferation	J:224370
	decreased length of long bones	J:224370
	delayed endochondral bone ossification	J:224370
	disorganized long bone epiphyseal plate	J:224370
	hematoma	J:224370
	increased chondrocyte apoptosis	J:224370
	neonatal lethality, complete penetrance	J:224370
	short femur	J:224370
	short humerus	J:224370
	short limbs	J:224370
	short radius	J:224370
	short scapula	J:224370
	short sternum	J:224370
	short tibia	J:224370
	short ulna	J:224370
	small clavicle	J:224370
	sternebra fusion	J:224370
	wide sternum	J:224370
Fermt2^{tm1a(EUCOMM)Wtsi}/Fermt2⁺ involves: C57BL/6N	normal endocrine/exocrine gland phenotype	J:219946
Fermt2^tm1Ref/Fermt2^tm1Ref Not Specified	abnormal cell adhesion	J:134768
	abnormal embryonic epiblast morphology	J:134768
	abnormal germ layer development	J:134768
	embryonic lethality between implantation and somite formation, complete penetrance	J:134768

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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