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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Usp1
ubiquitin specific peptidase 1
MGI:2385198
33 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Usp1tm1.1Ada/Usp1tm1.1Ada
C57BL/6-Usp1tm1.1Ada 		abnormal male germ cell morphology J:146616
abnormal spermatid morphology J:146616
abnormal spermatocyte morphology J:146616
abnormal spermatogonia morphology J:146616
cyanosis J:146616
decreased body weight J:146616
decreased bone marrow cell number J:146616
decreased oocyte number J:146616
edema J:146616
increased mortality induced by gamma-irradiation J:146616
induced chromosome breakage J:146616
male infertility J:146616
oligozoospermia J:146616
postnatal lethality, incomplete penetrance J:146616
reduced female fertility J:146616
seminiferous tubule degeneration J:146616
small testis J:146616
Usp1tm1b(KOMP)Wtsi/Usp1tm1b(KOMP)Wtsi
C57BL/6N-Usp1tm1b(KOMP)Wtsi/Wtsi 		abnormal eyelid aperture J:211773
abnormal snout morphology J:211773
decreased body length J:211773
decreased erythrocyte cell number J:211773
increased blood urea nitrogen level J:211773
increased circulating creatinine level J:211773
increased circulating insulin level J:211773
increased circulating potassium level J:211773
increased mean corpuscular hemoglobin J:211773
Usp1tm1d(KOMP)Wtsi/Usp1tm1d(KOMP)Wtsi
involves: C57BL/6N 		abnormal osteoid morphology J:207363
decreased bone mineral density J:207363
decreased bone volume J:207363
decreased circulating alkaline phosphatase level J:207363
delayed bone ossification J:207363
increased bone resorption J:207363
normal skeleton phenotype J:207363
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory