Kmt5c Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kmt5c
lysine methyltransferase 5C
MGI:2385262

15 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Kmt5b^tm1.1Jnw/Kmt5b^tm1.1Jnw Kmt5c^tm1.1Jnw/Kmt5c^tm1.1Jnw involves: 129 * C57BL/6J	abnormal cell cycle	J:139510
	abnormal DNA repair	J:139510
	abnormal pulmonary alveolus morphology	J:139510
	decreased body size	J:139510
	decreased fibroblast proliferation	J:139510
	early cellular replicative senescence	J:139510
	increased cellular sensitivity to hydroxyurea	J:139510
	increased cellular sensitivity to ultraviolet irradiation	J:139510
	neonatal lethality, complete penetrance	J:139510
	prenatal lethality, incomplete penetrance	J:139510
Kmt5b^tm1Jnw/Kmt5b^tm1Jnw Kmt5c^tm1.1Jnw/Kmt5c^tm1.1Jnw Commd10^{Tg(Vav1-icre)A2Kio}/Commd10⁺ involves: 129/Sv * C57BL/6J * C57BL/10 * CBA/Ca	abnormal class switch recombination	J:139510
	abnormal lymphopoiesis	J:139510
	decreased B cell number	J:139510
	decreased double-positive T cell number	J:139510
	normal immune system phenotype	J:139510

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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