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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tpcn2
two pore segment channel 2
MGI:2385297
12 phenotypes from 5 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ins1tm1.1(cre)Thor/Ins1+
Tpcn2tm1c(EUCOMM)Hmgu/Tpcn2tm1c(EUCOMM)Hmgu
involves: C57BL/6J * C57BL/6N 		no abnormal phenotype detected J:235705
Tpcn2em1Lwbch/Tpcn2+
C57BL/6J-Tpcn2em1Lwbch 		abnormal lysosome physiology J:332654
abnormal retina melanocyte morphology J:332654
decreased eye pigmentation J:332654
decreased tail pigmentation J:332654
diluted coat color J:332654
vision/eye phenotype J:332654
Tpcn2em1Lwbch/Tpcn2em1Lwbch
C57BL/6J-Tpcn2em1Lwbch 		abnormal lysosome morphology J:332654
abnormal lysosome physiology J:332654
abnormal retina melanocyte morphology J:332654
decreased eye pigmentation J:332654
decreased tail pigmentation J:332654
diluted coat color J:332654
normal vision/eye phenotype J:332654
Tpcn2Gt(YHD437)Byg/Tpcn2Gt(YHD437)Byg
involves: 129P2/OlaHsd * C57BL/6 		abnormal pancreatic beta cell physiology J:149472
Tpcn2tm1b(EUCOMM)Hmgu/Tpcn2tm1b(EUCOMM)Hmgu
C57BL/6N-Tpcn2tm1b(EUCOMM)Hmgu/H 		increased circulating triglyceride level J:211773
increased eosinophil cell number J:211773
Tpcn2tm1Lex/Tpcn2tm1Lex
B6;129S5-Tpcn2tm1Lex/Orl 		no abnormal phenotype detected J:82809
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory