Cyp2c70 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cyp2c70
cytochrome P450, family 2, subfamily c, polypeptide 70
MGI:2385878

22 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cyp2c70^em1Sjka/Cyp2c70^em1Sjka C57BL/6-Cyp2c70^em1Sjka	abnormal bile salt homeostasis	J:330641
	abnormal hepatobiliary system morphology	J:330641
	abnormal liver morphology	J:330641
	decreased body weight	J:330641
	increased bile salt level	J:330641
	increased circulating alanine transaminase level	J:330641
	increased circulating alkaline phosphatase level	J:330641
	increased circulating aspartate transaminase level	J:330641
	increased liver weight	J:330641
	increased spleen weight	J:330641
	liver fibrosis	J:330641
	liver inflammation	J:330641
Cyp2c70^em1Utr/Cyp2c70^em1Utr C57BL/6J-Cyp2c70^em1Utr	abnormal bile duct morphology	J:302190
	abnormal bile salt homeostasis	J:302190
	abnormal enzyme/coenzyme activity	J:302190
	abnormal liver morphology	J:302190
	decreased bile salt level	J:302190
	decreased feces bile salt level	J:302190
	decreased intestinal cholesterol absorption	J:302190
	hepatic necrosis	J:302190
	increased circulating alanine transaminase level	J:302190
	increased circulating alkaline phosphatase level	J:302190
	increased circulating cholesterol level	J:302190
	increased liver cholesterol level	J:302190
	increased liver weight	J:302190
	liver inflammation	J:302190
	premature death	J:302190
	reduced fertility	J:302190

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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