About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Picalm
phosphatidylinositol binding clathrin assembly protein
MGI:2385902
42 phenotypes from 8 alleles in 7 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Gt(ROSA)26Sortm1(cre/ERT2)Thl/0
Picalmtm1.1Tmae/Picalmtm1.1Tmae
involves: 129 * C57BL/6 * SJL 		abnormal erythropoiesis J:220728
diluted coat color J:220728
hypochromic microcytic anemia J:220728
Picalmfit1-494SB/Picalmfit1-494SB
involves: BALB/cRl 		anemia J:100221
decreased body size J:100221
Picalmfit1-764SB/Picalmfit1-764SB
involves: BALB/cRl 		anemia J:100221
decreased body size J:100221
Picalmfit1-3452SB/Picalmfit1-3452SB
involves: BALB/cRl 		anemia J:100221
decreased body size J:100221
Picalmfit1-4226SB/Picalmfit1-4226SB
involves: BALB/cRl 		anemia J:100221
decreased body size J:100221
Picalmfit1-4397SB/Picalmfit1-4397SB
involves: BALB/cRl 		anemia J:100221
decreased body size J:100221
Picalmtm1.1Tmae/Picalmtm1.1Tmae
Commd10Tg(Vav1-icre)A2Kio/Commd10+
involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * CBA * SJL 		abnormal iron homeostasis J:220728
decreased CD4-positive, alpha-beta T cell number J:220728
decreased CD8-positive, alpha-beta T cell number J:220728
decreased erythrocyte cell number J:220728
decreased mean corpuscular hemoglobin J:220728
decreased mean corpuscular volume J:220728
increased circulating erythropoietin level J:220728
microcytic anemia J:220728
reticulocytosis J:220728
Picalmtm1.1Tmae/Picalmtm1.1Tmae
Tg(Mx1-cre)1Cgn/0
involves: C57BL/6 * CBA * SJL 		abnormal erythrocyte morphology J:220728
abnormal erythropoiesis J:220728
abnormal iron homeostasis J:220728
decreased CD4-positive, alpha-beta T cell number J:220728
decreased CD8-positive, alpha-beta T cell number J:220728
decreased erythroblast number J:220728
decreased erythrocyte cell number J:220728
decreased hematocrit J:220728
decreased hemoglobin content J:220728
decreased mean corpuscular hemoglobin J:220728
decreased mean corpuscular volume J:220728
enlarged spleen J:220728
hypochromic microcytic anemia J:220728
impaired hematopoiesis J:220728
increased circulating erythropoietin level J:220728
increased circulating iron level J:220728
increased erythroblast number J:220728
increased red blood cell distribution width J:220728
reticulocytosis J:220728
Picalmtm1.2Tmae/Picalm+
involves: C57BL/6 * FVB/N 		microcytic anemia J:220728
Picalmtm1.2Tmae/Picalmtm1.2Tmae
involves: C57BL/6 * FVB/N 		abnormal embryonic tissue morphology J:220728
abnormal erythropoiesis J:220728
abnormal fetal liver hematopoietic progenitor cell morphology J:220728
decreased embryo size J:220728
decreased erythroblast number J:220728
increased erythroblast number J:220728
lethality throughout fetal growth and development, complete penetrance J:220728
Picalmtm1Towa/Picalmtm1Towa
B6.Cg-Picalmtm1Towa 		lethality, complete penetrance J:185312
Picalmtm1Towa/Picalmtm1Towa
involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj 		abnormal B cell differentiation J:185312
abnormal bone marrow cell morphology/development J:185312
abnormal cell physiology J:185312
abnormal erythrocyte physiology J:185312
abnormal erythropoiesis J:185312
abnormal hepatocyte physiology J:185312
abnormal iron homeostasis J:185312
decreased body size J:185312
decreased body weight J:185312
decreased bone marrow cell number J:185312
decreased embryo weight J:185312
decreased erythrocyte cell number J:185312
decreased erythroid progenitor cell number J:185312
decreased hemoglobin content J:185312
decreased mean corpuscular hemoglobin J:185312
decreased spleen B cell follicle number J:185312
enlarged spleen J:185312
fetal growth retardation J:185312
hemosiderosis J:185312
hypochromic microcytic anemia J:185312
postnatal growth retardation J:185312
postnatal lethality, incomplete penetrance J:185312
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory