C1qtnf5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

C1qtnf5
C1q and tumor necrosis factor related protein 5
MGI:2385958

33 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
C1qtnf5^{tm1(KOMP)Vlcg}/C1qtnf5^{tm1(KOMP)Vlcg} involves: C57BL/6NTac	normal adipose tissue phenotype	J:237401
	decreased circulating insulin level	J:237401
	decreased fasting circulating glucose level	J:237401
	decreased food intake	J:237401
	decreased liver triglyceride level	J:237401
	decreased susceptibility to diet-induced hepatic steatosis	J:237401
	normal growth/size/body region phenotype	J:237401
	normal homeostasis/metabolism phenotype	J:237401
	impaired gluconeogenesis	J:237401
	improved glucose tolerance	J:237401
	increased insulin secretion	J:237401
	increased insulin sensitivity	J:237401
C1qtnf5^{tm1.1(KOMP)Vlcg}/C1qtnf5⁺ B6N(Cg)-C1qtnf5^{tm1.1(KOMP)Vlcg}/J	abnormal retina morphology	J:211773
	increased fasting circulating glucose level	J:211773
C1qtnf5^{tm1.1(KOMP)Vlcg}/C1qtnf5^{tm1.1(KOMP)Vlcg} B6N(Cg)-C1qtnf5^{tm1.1(KOMP)Vlcg}/J	abnormal retina morphology	J:211773
C1qtnf5^tm1.1Geno/C1qtnf5^tm1.1Geno involves: 129 * C57BL/6J	no abnormal phenotype detected	J:180961
C1qtnf5^tm1.1Itl/C1qtnf5⁺ C57BL/6-C1qtnf5^tm1.1Itl	abnormal Bruch membrane morphology	J:171089
	abnormal cone electrophysiology	J:171089
	abnormal eye electrophysiology	J:171089
	abnormal ocular fundus morphology	J:171089
	abnormal photoreceptor inner segment morphology	J:171089
	abnormal retina cone cell inner segment morphology	J:171089
	abnormal retina cone cell morphology	J:171089
	abnormal retina photoreceptor morphology	J:171089
	abnormal retina pigment epithelium morphology	J:171089
	abnormal retina rod cell inner segment morphology	J:171089
	abnormal rod electrophysiology	J:171089
	decreased retina cone cell number	J:171089
	decreased total retina thickness	J:171089
	increased susceptibility to age-related retinal degeneration	J:171089
	increased vascular permeability	J:171089
	retina cone cell degeneration	J:171089
	short photoreceptor outer segment	J:171089
	thin retina outer nuclear layer	J:171089

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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