Card14 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Card14
caspase recruitment domain family, member 14
MGI:2386258

21 phenotypes from 5 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Card14^em1Tshu/Card14^em1Tshu C57BL/6-Card14^em1Tshu	decreased susceptibility to chemically induced skin inflammation	J:289239
Card14^em2Tshu/Card14⁺ involves: C57BL/6	abnormal gamma-delta T cell number	J:289239
	acanthosis	J:289239
	increased alpha-beta T cell number	J:289239
	postnatal lethality, incomplete penetrance	J:289239
	psoriasis	J:289239
	skin inflammation	J:289239
	thick epidermis	J:289239
Card14^em3Tshu/Card14⁺ involves: C57BL/6	psoriasis	J:289239
	skin inflammation	J:289239
	thick epidermis	J:289239
Card14^em9Lutzy/Card14⁺ C57BL/6J-Card14^em9Lutzy/J	abnormal blood vessel morphology	J:262723
	abnormal epidermal layer morphology	J:262723
	acanthosis	J:262723
	dry skin	J:262723
	flaky skin	J:262723
	hyperkeratosis	J:262723
	increased keratinocyte proliferation	J:262723
	orthokeratosis	J:262723
	parakeratosis	J:262723
	psoriasis	J:262723
	skin hyperplasia	J:262723
	skin inflammation	J:262723
	skin lesions	J:262723
	thick epidermis	J:262723
Card14^em9Lutzy/Card14^em9Lutzy C57BL/6J-Card14^em9Lutzy/J	decreased body size	J:262723
	dry skin	J:262723
	flaky skin	J:262723
	neonatal lethality, incomplete penetrance	J:262723
	postnatal lethality, complete penetrance	J:262723
Card14^tm1Lex/Card14^tm1Lex B6.129S-Card14^tm1Lex	decreased susceptibility to chemically induced skin inflammation	J:253409

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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