Gab3 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gab3
growth factor receptor bound protein 2-associated protein 3
MGI:2387324

9 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gab3^em1Khoe/Gab3^em1Khoe C57BL/6-Gab3^em1Khoe	abnormal mature NK cell morphology	J:291290
	abnormal NK cell physiology	J:291290
	abnormal uterine NK cell morphology	J:291290
	decreased NK cell number	J:291290
	dystocia	J:291290
	normal immune system phenotype	J:291290
	increased trophoblast giant cell number	J:291290
	normal mortality/aging	J:291290
Gab3^m1Khoe/Gab3^m1Khoe C57BL/6-Gab3^m1Khoe	abnormal mature NK cell morphology	J:291290
	abnormal NK cell physiology	J:291290
	abnormal uterine NK cell morphology	J:291290
	decreased NK cell number	J:291290
	dystocia	J:291290
	normal immune system phenotype	J:291290
	increased trophoblast giant cell number	J:291290
	normal mortality/aging	J:291290
Gab3^tm1Lrr/Y involves: 129S4/SvJae * C57BL/6	no abnormal phenotype detected	J:82505
Gab3^tm1Lrr/Gab3^tm1Lrr involves: 129S4/SvJae * C57BL/6	no abnormal phenotype detected	J:82505

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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