Wac Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Wac
WW domain containing adaptor with coiled-coil
MGI:2387357

20 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cd19^tm1(cre)Cgn/Cd19⁺ Wac^em2Cya/Wac^em2Cya B6.Cg-Cd19^tm1(cre)Cgn Wac^em2Cya	abnormal epigenetic regulation of gene expression	J:345327
	abnormal plasma cell differentiation	J:345327
	decreased B cell proliferation	J:345327
	decreased IgG1 level	J:345327
	decreased IgG2b level	J:345327
	decreased IgG3 level	J:345327
	decreased IgM level	J:345327
	decreased plasma cell number	J:345327
	normal hematopoietic system phenotype	J:345327
	impaired humoral immune response	J:345327
Wac^{tm2b(EUCOMM)Wtsi}/Wac⁺ C57BL/6N-Wac^{tm2b(EUCOMM)Wtsi}/Wtsi	abnormal cranium morphology	J:211773
	decreased circulating amylase level	J:211773
	decreased circulating triglyceride level	J:211773
	decreased eosinophil cell number	J:211773
	fusion of vertebral arches	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased Ly6C low monocyte number	J:211773
	increased mean platelet volume	J:211773
	increased monocyte cell number	J:211773
Wac^{tm2b(EUCOMM)Wtsi}/Wac^{tm2b(EUCOMM)Wtsi} C57BL/6N-Wac^{tm2b(EUCOMM)Wtsi}/Wtsi	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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