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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		B9d2
B9 protein domain 2
MGI:2387643
116 phenotypes from 2 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
B9d2/Tgfb1tm1Flv/B9d2+
Tg(Cd4-cre)1Cwi/0
involves: 129S6/SvEvTac * C57BL/6 * DBA/2 		abnormal T-helper 17 cell differentiation J:169839
B9d2/Tgfb1tm1Flv/B9d2+
Tg(CD207-cre)1Dhka/?
involves: 129S6/SvEvTac * C57BL/6J * SJL/J 		decreased Langerhans cell number J:126147
B9d2/Tgfb1tm1Flv/B9d2+
Foxp3tm4(YFP/icre)Ayr/Foxp3+
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ 		normal growth/size/body region phenotype J:169839
normal immune system phenotype J:169839
increased regulatory T cell number J:169839
B9d2/Tgfb1tm1Flv/B9d2+
Tnfrsf4tm2(cre)Nik/Tnfrsf4+
involves: 129S6/SvEvTac * 129X1/SvJ 		abnormal enterocyte proliferation J:169839
abnormal T cell differentiation J:169839
cachexia J:169839
colitis J:169839
decreased susceptibility to experimental autoimmune encephalomyelitis J:169839
decreased T-helper 17 cell number J:169839
increased regulatory T cell number J:169839
increased T-helper 1 cell number J:169839
liver inflammation J:169839
lung inflammation J:169839
B9d2/Tgfb1tm1Flv/B9d2/Tgfb1tm1Flv
Tg(Cd4-cre)1Cwi/?
involves: 129S6/SvEvTac * C57BL/6 * DBA/2 		abnormal inflammatory response J:123547
B9d2/Tgfb1tm1Flv/B9d2/Tgfb1tm1Flv
Tg(Cd4-cre)1Cwi/0
involves: 129S6/SvEvTac * C57BL/6 * SJL 		abnormal regulatory T cell physiology J:204761
B9d2/Tgfb1tm1Flv/B9d2/Tgfb1tm1Flv
Tg(CD207-cre)1Dhka/?
involves: 129S6/SvEvTac * C57BL/6J * SJL/J 		decreased Langerhans cell number J:126147
B9d2tm1a(EUCOMM)Wtsi/B9d2tm1a(EUCOMM)Wtsi
C57BL/6N-B9d2tm1a(EUCOMM)Wtsi/Wtsi 		abdominal situs ambiguus J:239583
abnormal adenohypophysis morphology J:239583
abnormal adrenal gland morphology J:239583
abnormal atrioventricular cushion morphology J:239583
abnormal brain internal capsule morphology J:239583
abnormal brain morphology J:239583
abnormal brain vasculature morphology J:239583
abnormal choroid plexus morphology J:239583
abnormal diaphragm morphology J:239583
abnormal ductus venosus topology J:239583
abnormal ductus venosus valve topology J:239583
abnormal eye muscle morphology J:239583
abnormal forebrain morphology J:239583
abnormal heart position or orientation J:239583
abnormal hepatic vein morphology J:239583
abnormal hindbrain morphology J:239583
abnormal hypoglossal nerve topology J:239583
abnormal incisor morphology J:239583
abnormal infrahyoid muscle connection J:239583
abnormal interatrial septum morphology J:239583
abnormal intestine placement J:239583
abnormal intrathoracic topology of vagus nerve J:239583
abnormal liver morphology J:239583
abnormal maxilla morphology J:239583
abnormal mitral valve cusp morphology J:239583
abnormal Mullerian duct morphology J:239583
abnormal nasal septum morphology J:239583
abnormal neurohypophysis morphology J:239583
abnormal olfactory bulb morphology J:239583
abnormal optic chiasm morphology J:239583
abnormal optic cup morphology J:239583
abnormal optic stalk morphology J:239583
abnormal ovary morphology J:239583
abnormal pancreas morphology J:239583
abnormal pectinate muscle morphology J:239583
abnormal rib morphology J:239583
abnormal spinal cord morphology J:239583
abnormal subclavian artery origin J:239583
abnormal thymus topology J:239583
abnormal tongue epithelium morphology J:239583
abnormal umbilical vein topology J:239583
abnormal vertebral arch morphology J:239583
abnormal vertebral artery morphology J:239583
abnormal vertebral artery topology J:239583
abnormal vertebral body morphology J:239583
abnormal vitelline vein topology J:239583
abnormal Wolffian duct connection J:239583
absent adenohypophysis J:239583
absent ductus venosus valve J:239583
absent intrahepatic inferior vena cava segment J:239583
absent oculomotor nerve J:239583
absent segment of anterior cerebral artery J:239583
absent segment of posterior cerebral artery J:239583
absent upper incisors J:239583
accessory spleen J:239583
additional anastomosis between intracranial vertebral arteries J:239583
anastomosis between internal carotid artery and basilar artery J:239583
anomalous pulmonary venous connection J:239583
aortic arch coarctation J:239583
aphakia J:239583
bicuspid pulmonary valve J:239583
bifid ureter J:239583
blood in lymph vessels J:239583
common atrium J:239583
double inlet heart left ventricle J:239583
double outlet left ventricle J:239583
double outlet right ventricle J:239583
double ureter J:239583
dual inferior vena cava J:239583
ductus venosus stenosis J:239583
ectopic ovary J:239583
embryo cyst J:239583
embryo tumor J:239583
enlarged brain ventricles J:239583
enlarged lymphatic vessel J:239583
fusion of vertebral arches J:239583
heterotaxia J:239583
increased hemangioma incidence J:239583
intestinal/bowel diverticulum J:239583
inverse situs of great intrathoracic arteries J:239583
left pulmonary isomerism J:239583
left sided inferior vena cava J:239583
muscular ventricular septal defect J:239583
perimembraneous ventricular septal defect J:239583
persistent right 6th pharyngeal arch artery J:239583
persistent right dorsal aorta J:239583
polydactyly J:239583
preweaning lethality, complete penetrance J:211773
reduced sympathetic cervical ganglion size J:239583
short tongue J:239583
small pancreas J:239583
small spleen J:239583
small superior cervical ganglion J:239583
small superior vagus ganglion J:239583
subcutaneous edema J:239583
symmetric azygos veins J:239583
thin motoric part of trigeminal nerve J:239583
thin oculomotor nerve J:239583
thoracoschisis J:239583
transposition of great arteries J:239583
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory