Otop1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Otop1
otopetrin 1
MGI:2388363

17 phenotypes from 5 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Otop1^{em1(IMPC)Ccpcz}/Otop1^{em1(IMPC)Ccpcz} C57BL/6NCrl-Otop1^{em1(IMPC)Ccpcz}/Ccpcz	abnormal spleen morphology	J:211773
	abnormal thymus morphology	J:211773
	decreased body weight	J:211773
	enlarged thymus	J:211773
	increased circulating aspartate transaminase level	J:211773
Otop1^ied/Otop1^ied involves: C3HeB/FeJ * C57BL/6	abnormal posture	J:103243
	absent otoliths	J:103243
	decreased vertical activity	J:103243
	head tilt	J:103243
	normal hearing/vestibular/ear phenotype	J:103243
	impaired coordination	J:103243
	impaired righting response	J:103243
	impaired swimming	J:103243
Otop1^mlh/Otop1^mlh BALB/c-Otop1^mlh	head tilt	J:227974
Otop1^mlh/Otop1^mlh BALB/c-Otop1^mlh	impaired swimming	J:227974
Otop1^mlh/Otop1^mlh involves: BALB/cJ	abnormal motor capabilities/coordination/movement	J:82639
	absent otoliths	J:82639
	head tilt	J:82639
	impaired swimming	J:82639
Otop1^tlt/Otop1^tlt B6.Cg-Otop1^tlt/J	abnormal vestibular ganglion morphology	J:109174
	absent linear vestibular evoked potential	J:89392
	absent otoliths	J:49524, J:89392
	head tilt	J:49524
	normal hearing/vestibular/ear phenotype	J:49524
	impaired swimming	J:49524, J:89392
Otop1^tlt/Otop1^tlt STOCK Oca2^p-6H/Oca2^p-d	abnormal posture	J:30803
	head tilt	J:30803
	impaired swimming	J:30803
Otop1^tm1Dor/Otop1^tm1Dor Not Specified	abnormal vestibular system physiology	J:171566
	absent otoliths	J:171566
	normal hearing/vestibular/ear phenotype	J:171566
	impaired swimming	J:171566

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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