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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gprc6a
G protein-coupled receptor, family C, group 6, member A
MGI:2429498
31 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gprc6atm1.1(KOMP)Vlcg/Gprc6atm1.1(KOMP)Vlcg
C57BL/6N-Gprc6atm1.1(KOMP)Vlcg/Ucd 		increased hemoglobin content J:211773
increased thymus weight J:211773
Gprc6atm1.1Kry/Gprc6atm1.1Kry
Tg(Cyp17a1-icre)AJako/0
involves: C57BL/6J 		decreased epididymis weight J:170888
decreased seminal vesicle weight J:170888
decreased testis weight J:170888
increased male germ cell apoptosis J:170888
oligozoospermia J:170888
small testis J:170888
Gprc6atm1Ldq/Gprc6atm1Ldq
involves: 129X1/SvJ * C57BL/6 		abnormal bone mineralization J:144372
abnormal circulating hormone level J:144372
abnormal circulating phosphate level J:144372
abnormal external male genitalia morphology J:144372
abnormal glucose homeostasis J:144372
abnormal glucose tolerance J:144372
abnormal internal male genitalia morphology J:144372
abnormal mammary gland development J:144372
abnormal urine homeostasis J:144372
decreased bone mineral density J:144372
decreased circulating insulin level J:144372
decreased circulating testosterone level J:144372
decreased lean body mass J:144372
decreased litter size J:144372
decreased seminal vesicle weight J:144372
decreased testis weight J:144372
hepatic steatosis J:144372
increased circulating estradiol level J:144372
increased circulating glucose level J:144372
increased insulin sensitivity J:144372
increased liver triglyceride level J:144372
increased urine beta2-microglobulin level J:144372
increased urine calcium level J:144372
increased urine phosphate level J:144372
increased white adipose tissue amount J:144372
small testis J:144372
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory