Irak2 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Irak2
interleukin-1 receptor-associated kinase 2
MGI:2429603

4 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Irak1^tm1.1Pcoh/? Irak2^tm1.1Pcoh/? involves: 129P2/OlaHsd * C57BL/6	decreased interferon-alpha secretion	J:205798
Irak1^tm1Jth/Y Irak2^tm1Aki/Irak2^tm1Aki involves: 129/Sv * C57BL/6	abnormal dendritic cell physiology	J:136290
	abnormal macrophage physiology	J:136290
	decreased susceptibility to endotoxin shock	J:136290

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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