Gbp5 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gbp5
guanylate binding protein 5
MGI:2429943

7 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gbp5^{em1(IMPC)Wtsi}/Gbp5^{em1(IMPC)Wtsi} C57BL/6N-Gbp5^{em1(IMPC)Wtsi}/WtsiIeg	increased circulating creatinine level	J:211773
Gbp5^tm1Tigm/Gbp5^tm1Tigm B6.Cg-Gbp5^tm1Tigm	decreased circulating interleukin-1 beta level	J:183942
	decreased circulating interleukin-18 level	J:183942
	decreased interleukin-1 beta secretion	J:183942
	decreased interleukin-18 secretion	J:183942
	impaired neutrophil recruitment	J:183942
	increased susceptibility to bacterial infection	J:183942

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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