Tbl1xr1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tbl1xr1
transducin (beta)-like 1X-linked receptor 1
MGI:2441730

37 phenotypes from 5 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ighg1^tm1(cre)Cgn/Ighg1⁺ Tbl1xr1^{tm1c(EUCOMM)Hmgu}/Tbl1xr1^{tm1c(EUCOMM)Hmgu} involves: 129P2/OlaHsd * C57BL/6J	abnormal B cell differentiation	J:292118
	abnormal spleen morphology	J:292118
Ighg1^tm1(cre)Cgn/Ighg1⁺ Tbl1xr1^tm1.1Meln/Tbl1xr1⁺ involves: 129P2/OlaHsd * C57BL/6J	abnormal B cell differentiation	J:292118
	abnormal spleen morphology	J:292118
Tbl1xr1^em2H/Tbl1xr1^em2H C57BL/6J-Tbl1xr1^em2H	normal behavior/neurological phenotype	J:335355
	decreased body fat mass	J:335355
	decreased body weight	J:335355
	decreased bone mineral content	J:335355
	decreased bone mineral density	J:335355
	normal homeostasis/metabolism phenotype	J:335355
	increased lean body mass	J:335355
	increased or absent threshold for auditory brainstem response	J:335355
Tbl1xr1^tm1.1Arte/Tbl1xr1^tm1.1Arte Tg(Fabp4-cre)1Rev/0 involves: C57BL/6	abnormal adipose tissue physiology	J:198124
	abnormal white adipose tissue morphology	J:198124
	impaired glucose tolerance	J:198124
	impaired lipolysis	J:198124
	increased abdominal fat pad weight	J:198124
	increased body weight	J:198124
	increased circulating leptin level	J:198124
	increased inguinal fat pad weight	J:198124
	increased liver triglyceride level	J:198124
	increased skeletal muscle triglyceride level	J:198124
	increased susceptibility to diet-induced obesity	J:198124
	increased total body fat amount	J:198124
	increased white fat cell number	J:198124
	increased white fat cell size	J:198124
	insulin resistance	J:198124
Tbl1xr1^{tm1b(EUCOMM)Hmgu}/Tbl1xr1⁺ C57BL/6N-Tbl1xr1^{tm1b(EUCOMM)Hmgu}/Ieg	abnormal auditory brainstem response	J:211773
	abnormal liver morphology	J:211773
	abnormal startle reflex	J:211773
	absent vibrissae	J:211773
	decreased circulating HDL cholesterol level	J:211773
	enlarged cecum	J:211773
	enlarged liver	J:211773
	enlarged ovary	J:211773
	increased blood urea nitrogen level	J:211773
	increased circulating phosphate level	J:211773
	increased heart weight	J:211773
Tbl1xr1^{tm1b(EUCOMM)Hmgu}/Tbl1xr1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Tbl1xr1^{tm1b(EUCOMM)Hmgu}/Ieg	abnormal auditory brainstem response	J:211773
	preweaning lethality, incomplete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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