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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gpr68
G protein-coupled receptor 68
MGI:2441763
24 phenotypes from 5 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gpr68tm1.1Aha/Gpr68tm1.1Aha
B6.129(C)-Gpr68tm1.1Aha 		decreased circulating insulin level J:189192
decreased insulin secretion J:189192
normal endocrine/exocrine gland phenotype J:189192
Gpr68tm1.1Yaxu/Gpr68tm1.1Yaxu
B6.Cg-Gpr68tm1.1Yaxu 		abnormal osteoclast differentiation J:149315
abnormal osteoclast physiology J:149315
normal adipose tissue phenotype J:149315
decreased tumor growth/size J:149315
normal immune system phenotype J:149315
normal skeleton phenotype J:149315
Gpr68tm1.1Yaxu/Gpr68tm1.1Yaxu
involves: 129S4/SvJae * C57BL/6 * FVB/N 		abnormal brown adipose tissue morphology J:149315
abnormal macrophage physiology J:149315
abnormal osteoclast differentiation J:149315
abnormal osteoclast physiology J:149315
decreased macrophage cell number J:149315
decreased tumor growth/size J:149315
increased brown adipose tissue amount J:149315
increased monocyte cell number J:149315
normal skeleton phenotype J:149315
Gpr68tm1Aha/Gpr68tm1Aha
B6.129-Gpr68tm1Aha 		decreased circulating glucagon level J:189192
decreased circulating glucose level J:189192
decreased circulating insulin level J:189192
decreased insulin secretion J:189192
normal endocrine/exocrine gland phenotype J:189192
normal homeostasis/metabolism phenotype J:189192
normal immune system phenotype J:146233
increased insulin sensitivity J:189192
Gpr68tm1Dgen/Gpr68tm1Dgen
B6.129P2-Gpr68tm1Dgen 		abnormal kidney physiology J:232321
normal renal/urinary system phenotype J:232321
normal respiratory system phenotype J:224758
Gpr68tm1Yaxu/Gpr68tm1Yaxu
involves: C57BL/6 		abnormal brown adipose tissue morphology J:149315
abnormal macrophage physiology J:149315
abnormal osteoclast differentiation J:149315
abnormal osteoclast physiology J:149315
decreased brown adipose tissue amount J:149315
decreased monocyte cell number J:149315
increased tumor growth/size J:149315
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory