Washc4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Washc4
WASH complex subunit 4
MGI:2441787

24 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Washc4^em1(IMPC)J/Washc4⁺ C57BL/6NJ-Washc4^em1(IMPC)J/Mmjax	hyperactivity	J:211773
Washc4^em1(IMPC)J/Washc4⁺ C57BL/6NJ-Washc4^em1(IMPC)J/Mmjax	increased fasting circulating glucose level	J:211773
Washc4^em1(IMPC)J/Washc4^em1(IMPC)J C57BL/6NJ-Washc4^em1(IMPC)J/Mmjax	abnormal egg cylinder morphology	J:279207
	absent head fold	J:279207
	absent primitive node	J:279207
	decreased embryo size	J:279207
	embryonic growth arrest	J:279207
	embryonic lethality between implantation and placentation, complete penetrance	J:279207
	embryonic lethality prior to organogenesis	J:211773
	failure of primitive streak formation	J:279207
	failure to gastrulate	J:279207
	preweaning lethality, complete penetrance	J:211773
Washc4^em1Ssod/Washc4^em1Ssod involves: C57BL/6J * SJL/J	abnormal excitatory synapse morphology	J:303795
	abnormal gait	J:303795
	abnormal lysosome morphology	J:303795
	abnormal motor capabilities/coordination/movement	J:303795
	abnormal protein level	J:303795
	fast extinction of fear memory	J:303795
	impaired coordination	J:303795
	impaired cued conditioning behavior	J:303795
	impaired limb coordination	J:303795
	increased neuron apoptosis	J:303795
	long stride length	J:303795
	lysosomal protein accumulation	J:303795

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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