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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Arhgef11
Rho guanine nucleotide exchange factor 11
MGI:2441869
16 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Arhgef11tm1.1Mak/Arhgef11tm1.1Mak
B6.129P2(C)-Arhgef11tm1.1Mak 		abnormal glucose homeostasis J:233950
abnormal white adipose tissue physiology J:233950
abnormal white fat cell differentation J:233950
decreased body weight J:233950
decreased percent body fat/body weight J:233950
decreased susceptibility to diet-induced non-insulin dependent diabetes J:233950
decreased susceptibility to diet-induced obesity J:233950
decreased white adipose tissue mass J:233950
decreased white fat cell number J:233950
hyperactivity J:233950
increased oxygen consumption J:233950
increased respiratory quotient J:233950
increased stereotypic behavior J:233950
Arhgef11tm1b(KOMP)Wtsi/Arhgef11tm1b(KOMP)Wtsi
C57BL/6N-Arhgef11tm1b(KOMP)Wtsi/H 		abnormal retina morphology J:211773
increased aggression J:211773
Arhgef11tm1Sgkd/Arhgef11tm1Sgkd
involves: 129 * C57BL/6J 		no abnormal phenotype detected J:198274
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory